Davion T, Delamarre J, Sallebert S, Ducroix J P, Dusehu E, Capron J P
Gastroenterol Clin Biol. 1987 May;11(5):424-8.
We report the case of a 43 year-old Portuguese woman, hospitalized for long-standing fever, fatigue and weight-loss. Biologic investigation demonstrated anicteric cholestasis. Abdominal plain film showed a single hepatic calcification; computerized tomography and ultrasonography of the liver led to the discovery of a large mass, centered by the calcification. C. T.-guided biopsy showed caseiform necrosis, surrounded by histiocytic and lymphocytic cells. Brucella agglutination tests were negative at the beginning of the illness but became positive secondarily. The germ was not isolated from the hepatic fragment. The melitine intradermo-reaction was positive. Outcome was rapidly favorable with antibiotic treatment. Analysis of the 14 previously published cases showed that the most constant features were the hepatic calcifications and the epidemiologic context.
我们报告了一名43岁葡萄牙女性的病例，她因长期发热、疲劳和体重减轻而住院。生物学检查显示无黄疸型胆汁淤积。腹部平片显示肝脏有一处钙化；肝脏的计算机断层扫描和超声检查发现了一个以钙化为中心的大肿块。CT引导下活检显示干酪样坏死，周围有组织细胞和淋巴细胞。布鲁氏菌凝集试验在疾病初期为阴性，但后来转为阳性。在肝脏组织中未分离出病菌。布鲁菌素皮内反应呈阳性。经抗生素治疗后病情迅速好转。对之前发表的14例病例的分析表明，最常见的特征是肝脏钙化和流行病学背景。
