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急性肢体缺血的最佳治疗方法是什么?

What Is the Best Treatment for Acute Limb Ischemia?

机构信息

Division of Vascular & Endovascular Surgery, Boston University School of Medicine 85 East Concord Street, Suite 3000, Boston, MA 02118, USA.

Division of Vascular & Endovascular Surgery, Boston University School of Medicine 85 East Concord Street, Suite 3000, Boston, MA 02118, USA.

出版信息

Adv Surg. 2022 Sep;56(1):287-304. doi: 10.1016/j.yasu.2022.03.004.

DOI:10.1016/j.yasu.2022.03.004
PMID:36096573
Abstract

Acute limb ischemia (ALI) is a vascular emergency associated with high rates of limb loss and mortality. Management of these patients is challenging given the severe systemic illness resulting from tissue ischemia and the high incidence of preexisting comorbid conditions and underlying peripheral arterial disease. Expeditious diagnosis, anticoagulation, and revascularization are of utmost importance in reducing morbidity. Revascularization may be accomplished using open, endovascular, or hybrid techniques. Approach to revascularization depends on the severity of ischemia, location of occlusion, cause, chance of recovery, comorbidities, and available resources.

摘要

急性肢体缺血(ALI)是一种与高截肢率和死亡率相关的血管急症。由于组织缺血引起的严重系统性疾病以及预先存在的合并症和潜在外周动脉疾病的高发生率,这些患者的管理具有挑战性。迅速诊断、抗凝和血运重建对于降低发病率至关重要。血运重建可以通过开放、血管内或杂交技术来完成。血运重建的方法取决于缺血的严重程度、闭塞的位置、原因、恢复的机会、合并症和可用资源。

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引用本文的文献

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Acute limb ischemia in the elderly: Determining the mortality factors.老年人急性肢体缺血:确定死亡因素。
Turk Gogus Kalp Damar Cerrahisi Derg. 2025 Jan 31;33(1):1-11. doi: 10.5606/tgkdc.dergisi.2025.27027. eCollection 2025 Jan.
2
Percutaneous thrombectomy for acute limb ischemia is associated with equivalent limb and mortality outcomes compared with open thrombectomy.经皮血栓切除术治疗急性肢体缺血与开放血栓切除术相比,具有同等的肢体和死亡率结局。
J Vasc Surg. 2024 May;79(5):1151-1162.e3. doi: 10.1016/j.jvs.2024.01.014. Epub 2024 Jan 13.
3
Effect of miR-206 on lower limb ischemia-reperfusion injury in rat and its mechanism.
miR-206 对大鼠下肢缺血再灌注损伤的作用及其机制。
Sci Rep. 2023 Dec 7;13(1):21574. doi: 10.1038/s41598-023-48858-z.
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Acute Coronary Syndrome: Disparities of Pathophysiology and Mortality with and without Peripheral Artery Disease.急性冠状动脉综合征:合并与不合并外周动脉疾病时病理生理学及死亡率的差异
J Pers Med. 2023 Jun 2;13(6):944. doi: 10.3390/jpm13060944.