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64 岁女性,以小脑出血症状起病的肺炎链球菌性脑膜炎的疑难病例报告。

A Challenging Case of Streptococcus pneumoniae Meningitis in a 64-Year-Old Woman Who Presented with Symptoms of Cerebellar Hemorrhage.

机构信息

Department of Internal Medicine, Tokyo Bay Urayasu Ichikawa Medical Center, Urayasu, Chiba, Japan.

出版信息

Am J Case Rep. 2022 Sep 13;23:e937139. doi: 10.12659/AJCR.937139.

DOI:10.12659/AJCR.937139
PMID:36097399
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9483238/
Abstract

BACKGROUND There is a recognized association between bacterial meningitis and intracranial hemorrhage. However, acute neurological symptoms at presentation, with confirmation of hemorrhage on imaging, may delay further investigations, including blood culture for diagnosing an infection. This report presents a challenging case of Streptococcus pneumoniae meningitis in a 64-year-old woman who presented with symptoms of cerebellar hemorrhage. CASE REPORT This report describes a 64-year-old woman who had a medical history of untreated diabetes mellitus. She was brought to our hospital with headache and impaired consciousness, complicated with fever. Based on the hemorrhage in the left cerebellar hemisphere detected in the head CT findings, the patient was initially diagnosed with cerebellar hemorrhage. However, a positive blood culture after 12 hours of admission made the physician consider a central nervous system infection as the cause of the hemorrhage and perform a lumbar puncture. Therefore, the patient was diagnosed with acute bacterial meningitis caused by Streptococcus pneumoniae, and antibiotic treatment was started immediately. Although her general condition improved after antibiotic treatment, her mental status did not improve completely. CONCLUSIONS This report highlights that the clinicians should be aware that bacterial meningitis may result in intracranial hemorrhage. Patients with symptoms of a hemorrhagic stroke should be thoroughly investigated to avoid a delay in the treatment of infection.

摘要

背景

细菌性脑膜炎与颅内出血之间存在公认的关联。然而,在出现急性神经症状并通过影像学证实出血时,可能会延迟进一步的检查,包括血液培养以诊断感染。本报告介绍了一例具有挑战性的 64 岁女性肺炎链球菌性脑膜炎病例,该患者表现为小脑出血的症状。

病例报告

本报告描述了一位 64 岁的女性,她患有未经治疗的糖尿病病史。因头痛和意识障碍,伴有发热,被送至我院。根据头部 CT 检查结果显示的左侧小脑半球出血,最初诊断为小脑出血。然而,入院 12 小时后血液培养阳性,使医生考虑将中枢神经系统感染作为出血的原因,并进行腰椎穿刺。因此,该患者被诊断为由肺炎链球菌引起的急性细菌性脑膜炎,并立即开始抗生素治疗。尽管患者在抗生素治疗后一般状况改善,但精神状态并未完全恢复。

结论

本报告强调了临床医生应意识到细菌性脑膜炎可能导致颅内出血。对于有出血性中风症状的患者,应进行彻底检查,以避免延误感染的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2d5/9483238/f1e934efa818/amjcaserep-23-e937139-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2d5/9483238/24919a0f98b2/amjcaserep-23-e937139-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2d5/9483238/f1e934efa818/amjcaserep-23-e937139-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2d5/9483238/24919a0f98b2/amjcaserep-23-e937139-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2d5/9483238/f1e934efa818/amjcaserep-23-e937139-g002.jpg

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Diagnostic error in the emergency department: learning from national patient safety incident report analysis.急诊科的诊断错误:从国家患者安全事件报告分析中学习。
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