Liang Y, Sun Y C
Department of Respiratory and Critical Care Medicine, Peking University Third Hospital, Beijing 100191, China.
Zhonghua Jie He He Hu Xi Za Zhi. 2022 Sep 12;45(9):920-925. doi: 10.3760/cma.j.cn112147-20220422-00342.
Acute exacerbation of chronic obstructive pulmonary disease (COPD) is an important part of the course of COPD. Patients with life-threatening acute exacerbation need to be admitted to the respiratory intensive care unit (RICU) for treatment in time. Malnutrition is common in COPD patients, and nutritional risk also has a high prevalence in patients with COPD exacerbation, which is closely associated with the clinical outcome and mortality of these patients. Identifying patients with high nutritional risk and providing appropriate nutritional treatment will help to improve survival rate, shorten length of hospital stay and reduce complications. This review describes the potential mechanisms of malnutrition in patients with COPD, the nutritional risk assessment of patients with COPD exacerbation hospitalized in RICU, the selection of nutritional treatment methods and formulas, and the relevant problems of nutritional management of patients required noninvasive ventilation, hoping to provide information for the optimization of nutritional treatment strategy for acute exacerbation of COPD and the exploration of clinical research in the future.
慢性阻塞性肺疾病(COPD)急性加重是COPD病程中的重要组成部分。有危及生命的急性加重的患者需要及时入住呼吸重症监护病房(RICU)进行治疗。营养不良在COPD患者中很常见,在COPD急性加重患者中营养风险也具有很高的患病率,这与这些患者的临床结局和死亡率密切相关。识别具有高营养风险的患者并提供适当的营养治疗将有助于提高生存率、缩短住院时间并减少并发症。本综述描述了COPD患者营养不良的潜在机制、入住RICU的COPD急性加重患者的营养风险评估、营养治疗方法和配方的选择以及需要无创通气的患者营养管理的相关问题,希望为优化COPD急性加重的营养治疗策略及未来临床研究探索提供信息。