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牛至作为一种有潜力的抗糖尿病药物来源。

Oregano as a potential source of antidiabetic agents.

机构信息

Cátedras CONACYT-Centro de Investigación en Alimentación y Desarrollo, AC, Culiacán, Sinaloa, Mexico.

Centro de Investigación en Alimentación y Desarrollo, AC, Culiacán, Sinaloa, Mexico.

出版信息

J Food Biochem. 2022 Dec;46(12):e14388. doi: 10.1111/jfbc.14388. Epub 2022 Sep 13.

DOI:10.1111/jfbc.14388
PMID:36098212
Abstract

Oregano is the name given to a great variety of herbs belonging mainly to the Lamiaceae and Verbenaceae botanical families. Oregano species are rich sources of phytochemicals such as phenolic compounds like rosmarinic acid, salvianolic acid, and luteolin, among others. A few articles have previously accessed some potential pharmacological bioactivities of oregano plants; however, none has focused on the antidiabetic studies. This review aims to summarize recent studies about the potential effect of phenolic compounds from oregano plant species. The reports were retrieved from electronic databases such as PubMed, Web of Science, National Center for Biotechnology Information (NCBI), and Scopus. In addition, articles related to the mentioned topics and published between 2004-2022 were selected. The results from this study show that the antidiabetic pharmacological reports of oregano phenolic compounds are mainly in vitro reports. Therefore, the diversity of oregano species yields a broad variety of phenolic constituents, where preclinical and clinical studies are strongly recommended.

摘要

牛至是一个主要属于唇形科和马鞭草科的多种草药的名称。牛至物种是植物化学物质的丰富来源,如酚类化合物,如迷迭香酸、丹酚酸和木犀草素等。以前有几篇文章探讨了牛至植物的一些潜在的药理生物活性;然而,没有一篇文章专注于糖尿病研究。本综述旨在总结牛至植物物种中酚类化合物的潜在作用的最新研究。报告从电子数据库中检索,如 PubMed、Web of Science、美国国家生物技术信息中心(NCBI)和 Scopus。此外,还选择了与上述主题相关的文章,并发表于 2004-2022 年之间。这项研究的结果表明,牛至酚类化合物的抗糖尿病药理作用主要是体外报告。因此,强烈建议进行牛至物种多样性的临床前和临床研究。

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Oregano as a potential source of antidiabetic agents.牛至作为一种有潜力的抗糖尿病药物来源。
J Food Biochem. 2022 Dec;46(12):e14388. doi: 10.1111/jfbc.14388. Epub 2022 Sep 13.
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