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小鼠的非联合性学习。吗啡和纳洛酮的作用。

Non-associative learning in the mouse. Effect of morphine and naloxone.

作者信息

Torre E, Fassino S, Ancona M

出版信息

Funct Neurol. 1986 Jul-Sep;1(3):279-84.

PMID:3609860
Abstract

The study evaluates the effect of morphine and naloxone on the process of non-associative learning in the mouse. Exploratory behavior was measured in thirty-six male albino mice (Suisse) placed on a Boissier and Simon hole-board, the procedure being repeated 24 h later after administration of naloxone and/or morphine, or bidistilled water i.p. The results show that the inhibitory effect naloxone has on the recollection process of the mnemonic traces appears to be masked by morphine.

摘要

该研究评估了吗啡和纳洛酮对小鼠非联想学习过程的影响。在放置于布瓦西耶和西蒙孔板上的36只雄性白化小鼠(瑞士种)中测量探索行为,在腹腔注射纳洛酮和/或吗啡或双蒸水24小时后重复该过程。结果表明,纳洛酮对记忆痕迹回忆过程的抑制作用似乎被吗啡掩盖了。

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