Olesen J
Funct Neurol. 1986 Oct-Dec;1(4):369-74.
Intracarotid injection of 133-Xenon and recording of wash out of radioactivity by 254 external stationary detectors was used to measure rCBF. Initial slope values were calculated by a computer, translated into color code and displayed on a TV-screen. rCBF in patients with epilepsy has been the object of former studies. Those who had a cortical focus showed corresponding high blood flow values during attack and during EEG paroxysms without clinical attacks. On the contrary, all other patients with a cortical focus were normal. Patients with complex partial seizures displayed no abnormalities interictally. During generalized epileptic seizures rCBF and metabolism doubled. Distinction must be made between patients with aura (classic migraine) and patients without aura (common migraine). In the latter CBF was normal or slightly elevated. In the former the aura symptoms are associated with reduced CBF. The reduction usually starts posteriorly and spreads gradually anteriorly. rCBF remains depressed for up to several hours into the headache phase. After 8-12 hours a reactive hyperemia may ensue. In common migraine rCBF remains normal throughout the attack. During classic migraine attacks rCBF is depressed whereas it is increased during epileptic attacks. Thus rCBF studies further strengthen the differences between epilepsy and migraine.
通过颈内注射133-氙并用254个外部固定探测器记录放射性物质的清除情况来测量局部脑血流量（rCBF）。初始斜率值由计算机计算得出，转换为颜色代码并显示在电视屏幕上。癫痫患者的rCBF一直是先前研究的对象。那些有皮质病灶的患者在发作期间以及脑电图阵发性发作（无临床发作）期间显示出相应的高血流量值。相反，所有其他有皮质病灶的患者均正常。复杂部分性发作的患者在发作间期无异常表现。在全身性癫痫发作期间，rCBF和代谢增加一倍。必须区分有先兆（典型偏头痛）的患者和无先兆（普通偏头痛）的患者。在后者中，脑血流量正常或略有升高。在前者中，先兆症状与脑血流量减少有关。减少通常从后部开始并逐渐向前扩散。rCBF在头痛期可持续数小时处于降低状态。8 - 12小时后可能会出现反应性充血。在普通偏头痛发作期间，rCBF在整个发作过程中保持正常。在典型偏头痛发作期间，rCBF降低，而在癫痫发作期间则升高。因此，rCBF研究进一步强化了癫痫和偏头痛之间的差异。
