Tfelt-Hansen P, Nielsen S L
Funct Neurol. 1986 Oct-Dec;1(4):499-502.
Treatment of migraine attacks and prophylactic treatment of migraine are discussed under the four headings: patient selection, trial design, evaluation of results and statistics. Furthermore, based on a previous multicenter prophylactic trial, crossover design was found four times more powerful than group comparison.
患者选择、试验设计、结果评估和统计学。此外,基于之前的一项多中心预防性试验,发现交叉设计的效力比组间比较强四倍。