Rita Levi Montalcini Department of Neurosciences, University of Turin, Italy. San Luigi Gonzaga University Hospital, Turin, Italy.
School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK. Hertfordshire Partnership University NHS Foundation Trust, Welwyn Garden City, UK. Centre for Psychedelic Research, Imperial College London, London, UK.
Braz J Psychiatry. 2023 Mar 11;45(1):28-37. doi: 10.47626/1516-4446-2022-2632.
Although an association has been found recently between obsessive-compulsive disorder and an increased risk of suicide, the prevalence of both suicidal ideation and attempts vary considerably and are generally assessed categorically. Our aims were to evaluate the prevalence of suicidal ideation and behaviors using a dimensional approach.
The sample included 129 patients with obsessive-compulsive disorder. Suicidality was assessed by administering the Columbia-Suicide Severity Rating Scale. Logistic and linear regressions were used to examine predictors of suicidal ideation, severe suicidal ideation, and suicidal behavior.
The lifetime prevalence of suicidal ideation and behaviors were 64.3% and 16.3%, respectively. Lifetime suicidal ideation was associated with the number of stressful life events, duration of illness, Hamilton Rating Scale for Depression scores, and family history of mood disorders. A family history of obsessive-compulsive disorder was associated with a lower probability of lifetime suicidal ideation. Severe suicidal ideation was related to greater severity of the most stressful life event, Hamilton Rating Scale for Depression scores, and longer duration of untreated illness. The probability of lifetime suicidal behavior was related to Hamilton Rating Scale for Anxiety scores, symmetry obsessions, and washing and checking compulsions. The probability of lifetime non-suicidal self-injurious behaviors was related to Hamilton Rating Scale for Anxiety scores.
Recognizing predictors of suicidal ideation/behavior is crucial to identifying patients at greater risk.
虽然最近发现强迫症与自杀风险增加之间存在关联，但自杀意念和自杀尝试的发生率差异很大，通常是分类评估的。我们的目的是使用维度方法评估自杀意念和行为的发生率。
该样本包括 129 名强迫症患者。通过哥伦比亚自杀严重程度评定量表评估自杀意念。使用逻辑回归和线性回归分析自杀意念、严重自杀意念和自杀行为的预测因素。
终生自杀意念和行为的发生率分别为 64.3%和 16.3%。终生自杀意念与生活应激事件数量、疾病持续时间、汉密尔顿抑郁评定量表评分和心境障碍家族史有关。强迫症家族史与较低的终生自杀意念发生率有关。严重自杀意念与最严重的生活应激事件的严重程度、汉密尔顿抑郁评定量表评分和未治疗疾病的持续时间有关。终生自杀行为的概率与汉密尔顿焦虑评定量表评分、对称强迫和洗涤检查强迫有关。终生非自杀性自伤行为的概率与汉密尔顿焦虑评定量表评分有关。
识别自杀意念/行为的预测因素对于确定风险较高的患者至关重要。
