Wallem Andrea, Felipe-Spada Natalia, Tomàs-Aliberas Jordi
Department of TMJ, School of Dentistry, Universitat Internacional de Catalunya, Barcelona, Spain.
Cranio. 2025 Mar;43(2):236-242. doi: 10.1080/08869634.2022.2120277. Epub 2022 Sep 13.
To identify the relationship between the use of selective serotonin reuptake inhibitors (SSRIs) as pharmacological treatment and the development of bruxism.
A systematic literature search was performed in PubMed and Scopus databases, which included articles written within the last 30 years. The working hypothesis was that there is a significant association between using SSRIs as an antidepressant medication and developing bruxism.
A total of four articles were included in the systematic review. All the articles are related to SSRI antidepressants and bruxism.
The results indicate that there is an apparent association between SSRI drug treatment and the development of bruxism. The methods of evaluation and analysis were different in each article and cannot be considered conclusive; however, there is sufficient information to elucidate the impact of SSRI drugs on the development of bruxism.
确定使用选择性5-羟色胺再摄取抑制剂（SSRIs）进行药物治疗与磨牙症发生之间的关系。
在PubMed和Scopus数据库中进行了系统的文献检索，纳入了过去30年内发表的文章。研究的假设是，使用SSRIs作为抗抑郁药物与磨牙症的发生之间存在显著关联。
系统评价共纳入4篇文章。所有文章均与SSRI类抗抑郁药和磨牙症相关。
结果表明，SSRI药物治疗与磨牙症的发生之间存在明显关联。每篇文章的评估和分析方法各不相同，不能视为结论性的；然而，有足够的信息来阐明SSRI药物对磨牙症发生的影响。
