接种 COVID-19 疫苗后儿童多系统炎症疾病疑似病例：病例报告和系统文献复习。
A Suspected Case of Multisystem Inflammatory Disease in Children Following COVID-19 Vaccination: A Case Report and Systematic Literature Review.
机构信息
From the Department of Pediatrics, Korea University Anam Hospital, Seoul, Republic of Korea.
出版信息
Pediatr Infect Dis J. 2022 Nov 1;41(11):e456-e460. doi: 10.1097/INF.0000000000003674. Epub 2022 Aug 25.
Abstract
Multisystem inflammatory syndrome in children (MIS-C) is rare but can be a potentially serious complication following SARS-CoV-2 infection in children. 1 Introduction of coronavirus disease 2019 (COVID-19) vaccines are effective in lowering the burden due to SARS-CoV-2. However, there have been reports of MIS occurrence following COVID-19 vaccination in adults. 2 The potential public health implication of MIS-C following COVID-19 vaccination is not clear in children. Our objective is to describe the spectrum of clinical disease, therapy, and outcomes of MIS-C following COVID-19 vaccination in children.
摘要
儿童多系统炎症综合征（MIS-C）较为罕见，但可能是儿童感染严重急性呼吸综合征冠状病毒 2 型（SARS-CoV-2）后的一种潜在严重并发症。1 冠状病毒病 2019（COVID-19）疫苗的推出，有效降低了 SARS-CoV-2 带来的负担。然而，有报道称 COVID-19 疫苗接种后成年人会出现 MIS-C。2 COVID-19 疫苗接种后儿童出现 MIS-C 的潜在公共卫生影响尚不清楚。我们的目的是描述 COVID-19 疫苗接种后儿童 MIS-C 的临床疾病谱、治疗方法和结局。
相似文献
1
A Suspected Case of Multisystem Inflammatory Disease in Children Following COVID-19 Vaccination: A Case Report and Systematic Literature Review.
Pediatr Infect Dis J. 2022 Nov 1;41(11):e456-e460. doi: 10.1097/INF.0000000000003674. Epub 2022 Aug 25.
2
Multisystem Inflammatory Syndrome in Children after SARS-CoV-2 Vaccination.
Emerg Infect Dis. 2022 May;28(5):990-993. doi: 10.3201/eid2805.212418. Epub 2022 Mar 11.
3
Multisystem Inflammatory Syndrome in a 12-Year-old Boy After mRNA-SARS-CoV-2 Vaccination.
Pediatr Infect Dis J. 2022 Mar 1;41(3):e93-e94. doi: 10.1097/INF.0000000000003442.
4
Reported cases of multisystem inflammatory syndrome in children aged 12-20 years in the USA who received a COVID-19 vaccine, December, 2020, through August, 2021: a surveillance investigation.
Lancet Child Adolesc Health. 2022 May;6(5):303-312. doi: 10.1016/S2352-4642(22)00028-1. Epub 2022 Feb 23.
5
Multisystem Inflammatory Syndrome Following SARS-CoV-2 Vaccination in Two Children.
Pediatrics. 2022 Aug 1;150(2). doi: 10.1542/peds.2021-055956.
6
Asymptomatic SARS-COV2 Infection or COVID-19 vaccination effect for severe multisystem inflammatory syndrome in a 6-year-old girl: case report and review of the literature.
Ital J Pediatr. 2024 Sep 27;50(1):194. doi: 10.1186/s13052-024-01758-y.
7
Multisystem Inflammatory Syndrome in Adults After Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Coronavirus Disease 2019 (COVID-19) Vaccination.
Clin Infect Dis. 2022 Aug 24;75(1):e741-e748. doi: 10.1093/cid/ciab936.
8
A case of multisystem inflammatory syndrome in adults following natural infection and subsequent immunization.
Int J Infect Dis. 2022 Mar;116:34-37. doi: 10.1016/j.ijid.2021.12.339. Epub 2021 Dec 24.
9
Multisystem inflammatory syndrome in children (MIS-C) possibly secondary to COVID-19 mRNA vaccination.
BMJ Case Rep. 2022 Mar 30;15(3):e247176. doi: 10.1136/bcr-2021-247176.
10
Multisystem Inflammatory Syndrome in an Adolescent Following SARS-CoV-2 Exposure Despite Three Doses of a COVID-19 Vaccine.
R I Med J (2013). 2022 Jun 1;105(5):41-45.
引用本文的文献
1
Humoral, T cell and immune gene expression responses to SARS-CoV-2 vaccination in a small group of children with previous MIS-C.
Vaccine. 2025 Aug 30;62:127461. doi: 10.1016/j.vaccine.2025.127461. Epub 2025 Jul 6.
2
Multisystem inflammatory syndrome in children (MIS-C): A nationwide collaborative study in the Greek population.
Eur J Pediatr. 2024 Apr;183(4):1693-1702. doi: 10.1007/s00431-023-05383-5. Epub 2024 Jan 12.
3
Multi-Inflammatory Syndrome in Children (MIS-C) in 2023: Is It Time to Forget about It?
Children (Basel). 2023 May 31;10(6):980. doi: 10.3390/children10060980.
4
Multisystem Inflammatory Syndrome in Children (MIS-C), Possibly Due to COVID-19 mRNA Vaccination.
Vaccines (Basel). 2023 May 6;11(5):956. doi: 10.3390/vaccines11050956.
本文引用的文献
1
Reported cases of multisystem inflammatory syndrome in children aged 12-20 years in the USA who received a COVID-19 vaccine, December, 2020, through August, 2021: a surveillance investigation.
Lancet Child Adolesc Health. 2022 May;6(5):303-312. doi: 10.1016/S2352-4642(22)00028-1. Epub 2022 Feb 23.
2
Multi inflammatory syndrome in a 16-year-old male following first dose of m-RNA COVID-19 vaccination.
Clin Infect Pract. 2022 Apr;14:100139. doi: 10.1016/j.clinpr.2022.100139. Epub 2022 Feb 15.
3
Multisystem Inflammatory-like Syndrome in a Child Following COVID-19 mRNA Vaccination.
Vaccines (Basel). 2021 Dec 30;10(1):43. doi: 10.3390/vaccines10010043.
4
Clinical practice guidelines in multisystem inflammatory syndrome (MIS-C) related to COVID-19: a critical review and recommendations.
World J Pediatr. 2022 Feb;18(2):83-90. doi: 10.1007/s12519-021-00499-w. Epub 2022 Jan 4.
5
A Case of Multisystem Inflammatory Syndrome in a 12-Year-old Male After COVID-19 mRNA Vaccine.
Pediatr Infect Dis J. 2022 Mar 1;41(3):e87-e89. doi: 10.1097/INF.0000000000003432.
6
Multisystem Inflammatory Syndrome in a Previously Vaccinated Adolescent Female With Sickle Cell Disease.
Pediatr Infect Dis J. 2022 Mar 1;41(3):e104-e105. doi: 10.1097/INF.0000000000003444.
7
Multisystem Inflammatory Syndrome in a 12-Year-old Boy After mRNA-SARS-CoV-2 Vaccination.
Pediatr Infect Dis J. 2022 Mar 1;41(3):e93-e94. doi: 10.1097/INF.0000000000003442.
8
Multisystem Inflammatory Syndrome in Children by COVID-19 Vaccination Status of Adolescents in France.
JAMA. 2022 Jan 18;327(3):281-283. doi: 10.1001/jama.2021.23262.
9
Autoantibody Release in Children after Corona Virus mRNA Vaccination: A Risk Factor of Multisystem Inflammatory Syndrome?
Vaccines (Basel). 2021 Nov 18;9(11):1353. doi: 10.3390/vaccines9111353.
10
Multisystem inflammatory syndrome in a male adolescent after his second Pfizer-BioNTech COVID-19 vaccine.
Acta Paediatr. 2022 Jan;111(1):125-127. doi: 10.1111/apa.16141. Epub 2021 Oct 28.
Zotero 插件