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腹腔镜辅助肛门直肠成形术与传统手术治疗肛门直肠畸形的围手术期结局比较:一项回顾性全国数据库研究。

Perioperative outcomes of laparoscopically assisted anorectoplasty versus conventional procedures for anorectal malformation: a retrospective nationwide database study.

机构信息

Department of Pediatric Surgery, Saitama Children's Medical Center, 1-2 Shintoshin, Chuo-ku, Saitama, 330-8777, Japan.

Department of Pediatric Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

出版信息

Pediatr Surg Int. 2022 Dec;38(12):1785-1791. doi: 10.1007/s00383-022-05234-8. Epub 2022 Sep 14.

Abstract

PURPOSE

This study aimed to compare the perioperative outcomes of laparoscopically assisted anorectoplasty (LAARP) and conventional procedures (CPs) for anorectal malformation (ARM) using a national inpatient database in Japan.

METHODS

Using the Diagnosis Procedure Combination database, we identified patients who underwent anorectoplasty for high- or intermediate-type ARMs from 2010 to 2019. Primary outcomes were postoperative rectal prolapse, anal stenosis, and general complications. Secondary outcomes were the duration of anesthesia and length of hospital stay. We performed 1:2 propensity score-matched analyses to compare the outcomes between the LAARP and CP groups.

RESULTS

We identified 1005 eligible patients, comprising 286 and 719 patients who underwent LAARP and CP, respectively. The propensity score-matched groups included 281 patients with LAARP and 562 with CP. The LAARP group showed a higher proportion of rectal prolapse (21.4% vs. 8.5%; odds ratio, 2.91; 95% confidence interval [CI], 1.89-4.48; p < 0.001) and longer duration of anesthesia (462 min vs. 365 min; difference, 90 min; 95% CI 43-137; p < 0.001) than the CP group. No significant differences were found in other outcomes.

CONCLUSION

LAARP had worse outcomes than CP in terms of rectal prolapse. Thus, we propose that LAARP may require technical refinement to improve patient outcomes.

摘要

目的

本研究旨在利用日本全国住院患者数据库,比较腹腔镜辅助肛门直肠成形术(LAARP)与传统手术(CPs)治疗肛门直肠畸形(ARM)的围手术期结果。

方法

使用诊断程序组合数据库,我们确定了 2010 年至 2019 年期间接受高位或中位 ARM 肛门直肠成形术的患者。主要结局是术后直肠脱垂、肛门狭窄和一般并发症。次要结局是麻醉持续时间和住院时间。我们进行了 1:2 的倾向评分匹配分析,以比较 LAARP 和 CP 组之间的结果。

结果

我们确定了 1005 名符合条件的患者,其中 286 名和 719 名患者分别接受了 LAARP 和 CP。在倾向评分匹配组中,LAARP 组包括 281 例患者,CP 组包括 562 例患者。LAARP 组直肠脱垂的比例较高(21.4% vs. 8.5%;优势比,2.91;95%置信区间 [CI],1.89-4.48;p<0.001),麻醉时间也较长(462 分钟 vs. 365 分钟;差异 90 分钟;95%CI 43-137;p<0.001)。其他结局无显著差异。

结论

与 CP 相比,LAARP 在直肠脱垂方面的结果较差。因此,我们提出 LAARP 可能需要技术改进以改善患者的结局。

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