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先天性肛门直肠畸形患者行后矢状入路肛门直肠成形术和腹腔镜辅助肛门直肠拖出术的临床结局和肛肠测压比较。

Comparison of clinical outcomes and anorectal manometry in patients with congenital anorectal malformations treated with posterior sagittal anorectoplasty and laparoscopically assisted anorectal pull through.

机构信息

Department of Pediatric Surgery, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

出版信息

J Pediatr Surg. 2009 Dec;44(12):2380-3. doi: 10.1016/j.jpedsurg.2009.07.064.

DOI:10.1016/j.jpedsurg.2009.07.064
PMID:20006031
Abstract

PURPOSE

The objective of this study is to analyze the clinical outcomes and anorectal manometry (AM) in infants with congenital high anorectal malformations treated with posterior sagittal anorectoplasty (PSARP) and laparoscopically assisted anorectal pull through (LAARP).

MATERIALS AND METHODS

From August 2005 to December 2008, 23 patients with congenital high anorectal malformations were randomly distributed into PSARP and LAARP groups. All of them underwent LAARP (11 cases) or PSARP (12 cases) at 2 or 3 months old. Clinical outcomes and results of anorectal manometry were compared between patients at the age of 17.4 +/- 4.9 and 19.3 +/- 6.2 months (P = .4270), respectively.

RESULTS

Kelly's clinical score for patients in LAARP and PSARP groups was 3.91 +/- 1.14 and 3.83 +/- 1.40 (P = .8827), respectively. Anal canal resting pressure and high-pressure zone length were 29.4 +/- 7.2 vs 23.4 +/- 6.5 mm Hg (P = .0479) and 14.9 +/- 3.0 vs 13.9 +/- 3.1 mm (P = .4414), respectively. Rectal anal inhibitory reflex was observed in 81.8% (9/11) and 83.3% (10/12) patients (P = 1.0000), respectively. The mean length of stay during the second hospitalization was 10.6 +/- 0.9 and 14.3 +/- 1.4 days (P < .0001), respectively.

CONCLUSIONS

Although no significant difference can be noted in clinical scoring between both groups, the results of anorectal manometry indicate that LAARP can significantly improve anal canal resting pressure and reduce the length of stay.

摘要

目的

本研究旨在分析经后路纵切肛门直肠成形术(PSARP)和腹腔镜辅助肛门直肠拖出术(LAARP)治疗先天性高位肛门直肠畸形婴儿的临床疗效和肛肠测压结果。

材料和方法

2005 年 8 月至 2008 年 12 月,23 例先天性高位肛门直肠畸形患儿被随机分为 PSARP 组和 LAARP 组。所有患儿均在 2~3 月龄时接受 LAARP(11 例)或 PSARP(12 例)治疗。比较两组患儿 17.4±4.9 月龄和 19.3±6.2 月龄时的临床疗效和肛肠测压结果(P=0.4270)。

结果

LAARP 组和 PSARP 组患儿的 Kelly 临床评分分别为 3.91±1.14 和 3.83±1.40(P=0.8827)。肛门静息压和高压区长度分别为 29.4±7.2mmHg 比 23.4±6.5mmHg(P=0.0479)和 14.9±3.0mm 比 13.9±3.1mm(P=0.4414)。81.8%(9/11)和 83.3%(10/12)的患儿可引出直肠肛门抑制反射(P=1.0000)。第二次住院期间的平均住院时间分别为 10.6±0.9d 和 14.3±1.4d(P<0.0001)。

结论

虽然两组患儿的临床评分无显著差异,但肛肠测压结果表明,LAARP 可显著提高肛门静息压,缩短住院时间。

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