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老年患者与尿毒症:透析的接受率和退出率

Old patients and uremia: rates of acceptance to and withdrawal from dialysis.

作者信息

Husebye D G, Kjellstrand C M

出版信息

Int J Artif Organs. 1987 May;10(3):166-72.

PMID:3610367
Abstract

We studied the entry of elderly uremic patients to chronic dialysis in the U.S. in 1979. We also reviewed long-term survival, causes of death, and risk factors for death in old patients on dialysis at one center for the period 1966 to 1983. A comparison of the number of patients at risk with the number entering dialysis in the United States in 1979 indicates that 80% of the patients aged 25-45 years, 30% of patients over the age of 65 years, and 6% of those over the age of 75 years entered dialysis during that period. Of 239 patients over the age of 70 years followed at the Regional Kidney Disease Program at Hennepin County Medical Center in Minneapolis, the seven-year cumulative survival was 17%. In this program withdrawal from dialysis was the commonest cause of death, accounting for 40% of all deaths. Age groups over 75 years, sex, time period, duration of dialysis, eight pre-existing degenerative diseases, living situation, family support, and site and type of dialysis were not risk factors for termination of dialysis, but living in a nursing home was. When compared to the young, total deaths and deaths from discontinuation were much higher, and this decision was made earlier. Half of the patients who died because dialysis was discontinued were competent and decided for themselves; the other half were incompetent and families and physicians made the decision.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

我们研究了1979年美国老年尿毒症患者开始接受慢性透析的情况。我们还回顾了1966年至1983年期间,一家中心接受透析治疗的老年患者的长期生存率、死亡原因及死亡风险因素。1979年美国处于风险中的患者数量与开始接受透析的患者数量对比表明,25至45岁的患者中有80%、65岁以上的患者中有30%以及75岁以上的患者中有6%在该时期开始接受透析。在明尼阿波利斯市亨内平县医疗中心区域肾病项目随访的239名70岁以上患者中,七年累积生存率为17%。在该项目中,停止透析是最常见的死亡原因,占所有死亡病例的40%。75岁以上年龄组、性别、时间段、透析时长、八种既往退行性疾病、生活状况、家庭支持以及透析地点和类型并非停止透析的风险因素,但住在养老院是。与年轻人相比,总死亡数及因停止透析导致的死亡数要高得多,且这一决定做出得更早。因停止透析而死亡的患者中有一半有行为能力并自行做出决定;另一半无行为能力,由家人和医生做出决定。(摘要截选于250词)

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