COVID-19 相关静脉血栓栓塞症：病例汇总分析。
Venous thromboembolism in COVID-19: A meta-summary of cases.
机构信息
From the Department of Internal Medicine (ALGhasab), Medical Collage, Ha'il University; from the Department of Medicine (Alharbi), College of Medicine, University of Ha'il, Ha'il; from the College of Medicine (Altamimi), King Saud University, Riyadh; from the Department of Surgery (ALMesned), Medical College, Qassim University, Buraydah, Kingdom of Saudi Arabia; and from the Department of Medicine (ALGhasab, Khetan), McMaster University, Canada.
出版信息
Saudi Med J. 2022 Sep;43(9):979-990. doi: 10.15537/smj.2022.43.9.20220316.
OBJECTIVES
To summarize cases of venous thromboembolism (VTE), including pulmonary embolism (PE) and deep vein thrombosis (DVT) among coronavirus disease (COVID-19) patients and discuss their symptoms, diagnostic method, clinical features, and prognosis.
METHODS
All major databases were searched for relevant studies published between December 1, 2019 and May 5, 2021.
RESULTS
A total of 233 articles were identified, 22 describing 48 patients were included. A total of 79.1% had PE and 20.9% had DVT. Most patients were men, with a mean age of 56 years. Comorbidities were present in 70.8%, and 85.4% had at least one risk factor of VTE. 56.3% had received anticoagulation therapy. Most patients were treated in the general ward. Complications occurred in 27.1% of the patients, and recovery was achieved in 80.4%.
CONCLUSION
Venous thromboembolism must be suspected even in patients who had received prior anticoagulant regimens or in stable cases, especially in males, the elderly, and patients with comorbidities and high D-dimer levels.
目的
总结冠状病毒病（COVID-19）患者静脉血栓栓塞症（VTE），包括肺栓塞（PE）和深静脉血栓形成（DVT）的病例，并讨论其症状、诊断方法、临床特征和预后。
方法
检索 2019 年 12 月 1 日至 2021 年 5 月 5 日期间发表的所有主要数据库中相关研究。
结果
共确定了 233 篇文章，其中 22 篇描述了 48 例患者纳入本研究。共有 79.1%的患者患有 PE，20.9%的患者患有 DVT。大多数患者为男性，平均年龄为 56 岁。合并症发生率为 70.8%，85.4%的患者至少存在一个 VTE 风险因素。56.3%的患者接受了抗凝治疗。大多数患者在普通病房接受治疗。27.1%的患者发生并发症，80.4%的患者恢复。
结论
即使在接受过抗凝治疗方案或病情稳定的患者中，也应怀疑发生静脉血栓栓塞症，尤其是男性、老年人以及存在合并症和高 D-二聚体水平的患者。
Zotero 插件