Rheumatology Unit, Meyer Children's University Hospital, Firenze, Italy.
Rheumatology Unit, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy.
Clin Exp Rheumatol. 2022 Sep;40(8):1560-1566. doi: 10.55563/clinexprheumatol/sian1b. Epub 2022 Sep 14.
The assessment of quality of life (QoL) in Behçet's disease (BD) patients has been a surrogate of disease outcomes, but a wider impact on the patient's lifestyle has not been considered. This systematic review aims to provide an overview of the existing tools specifically adopted to explore the QoL in BD patients.
A systematic literature review was conducted using 2 electronic databases, according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. A combination of BD and QoL-related search terms were used. All articles were screened by 3 independent reviewers for title, abstract and full text level. Studies investigating QoL in BD patients were included.
64 papers of 497 records were retained. Data about 7,449 patients with a BD diagnosis and QoL evaluation were collected. 47 different tools to evaluate QoL were detected. The mean number of tools adopted in each study was 2.14±1.34. General QoL and psychological and social impact were investigated in 68.75% and 54.69% respectively. The correlation with disease activity was investigated in 71.86%.
The assessment of QoL in BD patients may provide a fundamental measurement for health to evaluate the outcome of interventions for BD patients. The adoption of a single validated QoL tool, developed including the BD patient's perspective, may provide an accurate and effective assessment, ensure the comparison within different cohorts, and set standardised values to define QoL level in BD patients.
评估贝切特病（BD）患者的生活质量（QoL）是疾病结局的替代指标，但尚未考虑其对患者生活方式的更广泛影响。本系统评价旨在概述专门用于探索 BD 患者 QoL 的现有工具。
根据系统评价和荟萃分析的首选报告项目（PRISMA）指南，使用 2 个电子数据库进行系统文献检索。使用 BD 和 QoL 相关的搜索词组合。由 3 名独立审查员对标题、摘要和全文进行筛选。纳入研究 BD 患者生活质量的文章。
保留了 497 条记录中的 64 篇论文。共收集了 7449 例 BD 诊断和 QoL 评估患者的数据。共发现 47 种不同的 QoL 评估工具。每项研究中采用的工具数量平均值为 2.14±1.34。分别调查了 68.75%和 54.69%的一般 QoL 和心理社会影响。71.86%的研究调查了与疾病活动的相关性。
评估 BD 患者的 QoL 可能为评估 BD 患者干预措施的结果提供健康的基本衡量标准。采用包括 BD 患者观点的单一经过验证的 QoL 工具，可以提供准确有效的评估，确保在不同队列之间进行比较，并确定 BD 患者 QoL 水平的标准化值。
