Garlick P J
Hum Nutr Clin Nutr. 1987 May;41(3):165-76.
A method is proposed for calculating nutrient utilization rates from measurements of respiratory gas exchange by considering the balance of the elements C, O, H, N and S, without the need to define the pathways of intermediary metabolism. This approach enables the sources of error in the calculation of nutrient utilization to be readily identified, and their effect on precision to be assessed in different nutritional and metabolic states. Equations have been derived for calculating fat and carbohydrate utilization in the fed state. These are different from the conventional equations, which were intended for use in the fasted state. They take account of variations in the compositions of fat, carbohydrate and protein in the nutrients utilized, whether from the body stores during fasting or from the diet during feeding. Examples of the use of these equations show that failure to account adequately for the composition of food or nutritional support regimens can cause avoidable errors in the calculated rates of fat and carbohydrate utilization.
提出了一种通过考虑碳、氧、氢、氮和硫元素的平衡，根据呼吸气体交换测量值来计算营养物质利用率的方法，无需定义中间代谢途径。这种方法能够很容易地识别营养物质利用率计算中的误差来源，并评估其在不同营养和代谢状态下对精度的影响。已经推导了用于计算进食状态下脂肪和碳水化合物利用率的方程。这些方程与传统方程不同，传统方程旨在用于禁食状态。它们考虑了所利用营养物质中脂肪、碳水化合物和蛋白质组成的变化，无论是禁食期间来自身体储存还是进食期间来自饮食。这些方程的使用示例表明，未能充分考虑食物或营养支持方案的组成会导致脂肪和碳水化合物利用率计算中出现可避免的误差。
