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民事收治后阿片类药物使用的阿片类药物复发和 MOUD 结局。

Opioid relapse and MOUD outcomes following civil commitment for opioid use.

机构信息

Department of Psychology, College of the Holy Cross, Worcester, MA, USA.

Department of Health Law, Policy & Management, School of Public Health, Boston University, Boston, MA, USA.

出版信息

J Subst Abuse Treat. 2022 Nov;142:108873. doi: 10.1016/j.jsat.2022.108873. Epub 2022 Sep 9.

DOI:10.1016/j.jsat.2022.108873
PMID:36108441
Abstract

INTRODUCTION

Opioid use disorder (OUD) continues to present a major public health problem in the United States. Civil commitment for substance use is one mandatory form of treatment for severe opioid use that has become increasingly available in recent years, but empirical data on this approach are lacking. This study examines clinical outcomes of civil commitment in a sample of adults with severe opioid use.

METHODS

Participants were 121 persons with opioid use who were interviewed at the point of entry into civil commitment, then followed for 12 weeks after their release.

RESULTS

Prior to civil commitment, this sample exhibited serious substance use characteristics (including high rates of illicit opioid use, other substance use, and injection drug use), as well as mental health problems (diagnoses of depression and anxiety disorders). During follow-up, approximately 41 % of the sample reported at least one illicit opioid use day. More than 64 % of the sample reported at least one day of medication for opioid use disorder (MOUD) receipt, and participants were significantly less likely to use illicit opioids on days that they received MOUDs. No participants died during the follow-up period.

CONCLUSIONS

In this sample of persons with severe opioid use, clinical outcomes of civil commitment included illicit opioid relapse as well as varying levels of MOUD uptake. Civil commitment may be a viable method for short-term prevention of overdose for a subset of this vulnerable patient population.

摘要

简介

在美国,阿片类药物使用障碍(OUD)仍然是一个主要的公共卫生问题。民事承诺是治疗严重阿片类药物使用的强制性治疗形式之一,近年来这种形式越来越普及,但关于这种方法的经验数据却很缺乏。本研究考察了在一组严重阿片类药物使用者样本中,民事承诺的临床结果。

方法

参与者为 121 名接受阿片类药物使用治疗的成年人,他们在进入民事承诺时接受了访谈,然后在出院后的 12 周内接受了随访。

结果

在民事承诺之前,该样本表现出严重的物质使用特征(包括非法阿片类药物使用、其他物质使用和注射药物使用的高比率),以及心理健康问题(抑郁症和焦虑障碍的诊断)。在随访期间,大约 41%的样本报告了至少一天的非法阿片类药物使用。超过 64%的样本报告了至少一天的阿片类药物使用障碍(MOUD)药物治疗,并且参与者在接受 MOUD 治疗的日子里,使用非法阿片类药物的可能性明显降低。在随访期间,没有参与者死亡。

结论

在这个严重阿片类药物使用者的样本中,民事承诺的临床结果包括非法阿片类药物的复发以及 MOUD 的不同程度的接受。对于这一脆弱患者群体的一部分人来说,民事承诺可能是一种可行的短期预防过量用药的方法。

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