Ratnesh Kumar, Kumar Pawan, Arya Anamica
Department of General Surgery, Jawaharlal Nehru Medical College, Bhagalpur, Bihar, India.
Department of General Medicine, Jawaharlal Nehru Medical College, Bhagalpur, Bihar, India.
J Pharm Bioallied Sci. 2022 Jul;14(Suppl 1):S868-S871. doi: 10.4103/jpbs.jpbs_30_22. Epub 2022 Jul 13.
Surgery site infections (SSIs) are infections that arise in surgery for an operative wound infection surveillance within 30 days of surgery or 90 days after implant installation. JNMC, Bhagalpur, India, intended to look at the pre- and postoperative use of antibiotics.
Four hundred twelve patient charts were analyzed for four months in JNMC, Bhagalpur, India as part of a hospital-based cross-section study. The study covered all patients 13 years of age and older who had been admitted to the hospital and had undergone various surgeries. In addition, a value was preserved for the further multivariate analysis, using multiple logistic regressions, to study the association between the resulting variable and the predictor.
The general surgery operation included 152 of the 412 patients, while the remainder was for different operations. A single operative antibiotic was administered to the majority of patients, followed by two surgical prophylactic medications. Before the hospital was discharged, 40 of the patients experienced surgical site infections. In almost half of these cases, ceftriaxone and metronidazole were combined with SSIs. Emergency surgery patients were 2.6 times more likely to have a SSI than optional surgery patients. The SSIs were 2.5 times more likely in patients who were not given antibiotic prophylaxis. In our investigation, the protection against SSI was found to include clean-contaminated and contaminated wound types.
According to this study, the majority of patients received antimicrobial prophylaxis. In the hospital where the study was done, the total incidence of SSIs was 11.1%. The most frequently given antibiotic was ceftriaxone. The absence of prevention, wound type, and types of surgery has all been associated with SSI development.
手术部位感染（SSIs）是指在手术后30天内或植入物安装后90天内发生的手术伤口感染监测中的感染。印度巴格布尔的JNMC医院旨在研究抗生素的术前和术后使用情况。
作为一项基于医院的横断面研究的一部分，对印度巴格布尔的JNMC医院412份患者病历进行了为期四个月的分析。该研究涵盖了所有13岁及以上入院并接受各种手术的患者。此外，使用多元逻辑回归保留一个值用于进一步的多变量分析，以研究结果变量与预测因素之间的关联。
412名患者中的152名进行了普通外科手术，其余患者进行了不同的手术。大多数患者使用了单一手术抗生素，其次是两种手术预防性药物。在出院前，40名患者发生了手术部位感染。在几乎一半的这些病例中，头孢曲松和甲硝唑与手术部位感染相关。急诊手术患者发生手术部位感染的可能性是择期手术患者的2.6倍。未接受抗生素预防的患者发生手术部位感染的可能性是接受预防患者的2.5倍。在我们的调查中，发现对手术部位感染的预防包括清洁-污染和污染伤口类型。
根据这项研究，大多数患者接受了抗菌预防。在进行该研究的医院中，手术部位感染的总发生率为11.1%。最常用的抗生素是头孢曲松。缺乏预防、伤口类型和手术类型都与手术部位感染的发生有关。
