Lopez-Avila V, Wood R, Flanagan M, Scott R
J Chromatogr Sci. 1987 Jul;25(7):286-91. doi: 10.1093/chromsci/25.7.286.
Two wide-bore capillary columns are evaluated for their applicability to the purge-and-trap technique and GC/MS analysis of 34 volatile organics. Neither column is able to completely resolve all 34 compounds, as is also typical of the packed column; however, the analysis is faster than with the packed column (18 to 21 min compared to 30 min), and the column effluent is introduced directly into the mass spectrometer without requiring an open-split interface. Method precision, as assessed from the instrument response at a concentration of 50 micrograms/L per component, is better than +/- 5% for 41% of the compounds using the VOCOL column (diphenyl dimethyl polysiloxane with crosslinking moieties) and for 53% of the compounds using the 007 column (95% methyl 5% phenyl silicone). The instrument response is linear from 20 to 200 micrograms/L for most compounds, and the amounts loaded to either column without serious distortion of the peak shape or resolution can be as high as 5 micrograms per component. Because the VOCOL column resolved more compounds than the 007 column within approximately the same analysis time, this column is further tested for performance with groundwater samples.
对两根宽口径毛细管柱进行了评估，以确定它们对吹扫捕集技术以及34种挥发性有机物的气相色谱/质谱分析的适用性。与填充柱的情况一样，没有一根柱能够完全分离所有34种化合物；然而，该分析比填充柱更快（分别为18至21分钟和30分钟），并且柱流出物可直接引入质谱仪，无需开分流接口。根据各组分浓度为50微克/升时的仪器响应评估，使用VOCOL柱（带有交联部分的二苯基二甲基聚硅氧烷）时，41%的化合物方法精密度优于±5%，使用007柱（95%甲基5%苯基硅氧烷）时，53%的化合物方法精密度优于±5%。大多数化合物的仪器响应在20至200微克/升范围内呈线性，并且在不严重扭曲峰形或分辨率的情况下，加载到任一柱上的量可高达每组分5微克。由于在大约相同的分析时间内，VOCOL柱比007柱分离出更多的化合物，因此对该柱进行了地下水样品性能的进一步测试。
