Mäkelä E A, Vainionpää S, Vihtonen K, Mero M, Laiho J, Törmälä P, Rokkanen P
J Pediatr Orthop. 1987 Jul-Aug;7(4):415-20. doi: 10.1097/01241398-198707000-00007.
A polyglactin 910 rod 3.2 mm in diameter and 25 mm in length was driven in a drill hole in the intercondylar portion of the right femur across the central portion of the growth plate in 20 5-week-old rabbits. The follow-up times were 3, 6, 12, and 24 weeks. The distal femoral growth plates of both femurs were analyzed by radiographic, microradiographic, and oxytetracycline fluorescence, histological, and histomorphometric studies. Histomorphometric studies showed clear changes at injury site and appeared to be an excellent means of exact numerical description of the different cellular areas of the growth plate. Six weeks after implantation, a polyglactin 910 implant resulted in a growth disturbance similar to that of a drill hole of equal bore.
将一根直径3.2毫米、长度25毫米的聚乙醇酸910棒植入20只5周龄家兔右股骨髁间部分的钻孔中，使其穿过生长板的中央部分。随访时间为3周、6周、12周和24周。通过放射学、微放射学、土霉素荧光、组织学和组织形态计量学研究对双侧股骨远端生长板进行分析。组织形态计量学研究显示损伤部位有明显变化，似乎是对生长板不同细胞区域进行精确数值描述的极佳方法。植入6周后，聚乙醇酸910植入物导致的生长紊乱与同等孔径钻孔造成的相似。
