Mosen David M, Banegas Matthew P, Keast Erin M, Ertz-Berger Briar L
From Kaiser Permanente Center for Health Research, Portland (DMM, MPB, EMK); Northwest Permanente, Continuum of Care Department, Portland, OR (BLE-B)
From Kaiser Permanente Center for Health Research, Portland (DMM, MPB, EMK); Northwest Permanente, Continuum of Care Department, Portland, OR (BLE-B).
J Am Board Fam Med. 2022 Sep 16. doi: 10.3122/jabfm.2022.AP.210497.
Social isolation among older individuals is associated with poor health outcomes. However, less is known about the association between social isolation and memory loss, specifically among Medicare enrollees in large, integrated health care systems.
We conducted a cross-sectional, observational study. From a cohort of Medicare members aged 65 years and older at Kaiser Permanente Northwest (KPNW) who completed a health questionnaire, we compared self-reported memory loss of those who reported feeling lonely or socially isolated and those who did not, adjusting for demographic factors, health conditions, and use of health services in the 12 months before the survey.
Patients who reported sometimes experiencing social isolation were more likely than those who rarely or never experienced social isolation to report memory loss in both unadjusted (odds ratio [OR]: , 95% CI= , ) and adjusted (OR: , 95% CI= , ) logistic regression models. Similarly, those who reported social isolation often or always were more likely to report memory loss than those who reported rarely or never experiencing isolation in both unadjusted (OR: , 95% CI = , ) and adjusted logistic regression models (OR: , 95% CI = , ).
The strong association between social isolation and memory loss suggest the need to develop interventions to reduce isolation and to evaluate their effects on potential future memory loss.
老年人的社会孤立与健康状况不佳有关。然而，关于社会孤立与记忆力丧失之间的关联，人们了解较少，尤其是在大型综合医疗保健系统中的医疗保险参保者中。
我们进行了一项横断面观察性研究。从凯撒永久医疗集团西北分部（KPNW）年龄在65岁及以上且完成健康问卷的医疗保险成员队列中，我们比较了报告感到孤独或社会孤立者与未报告者的自我报告记忆力丧失情况，并对调查前12个月的人口统计学因素、健康状况和医疗服务使用情况进行了调整。
在未调整（优势比[OR]： ，95%置信区间= ， ）和调整（OR： ，95%置信区间= ， ）的逻辑回归模型中，报告有时经历社会孤立的患者比很少或从未经历社会孤立的患者更有可能报告记忆力丧失。同样，在未调整（OR： ，95%置信区间 = ， ）和调整后的逻辑回归模型（OR： ，95%置信区间 = ， ）中，报告经常或总是经历社会孤立的患者比报告很少或从未经历孤立的患者更有可能报告记忆力丧失。
社会孤立与记忆力丧失之间的强烈关联表明，需要制定干预措施以减少孤立，并评估其对未来潜在记忆力丧失的影响。
