Johnson R H, Robinson B J
J Neurol Neurosurg Psychiatry. 1987 Jun;50(6):738-42. doi: 10.1136/jnnp.50.6.738.
Three patients are described who presented with autonomic failure affecting predominantly one limb. Physiological studies revealed that there was sweating loss in the limb which appeared to be due to a preganglionic autonomic lesion and not to a sweat gland abnormality. In all three patients there was also evidence of failure of vasomotor control. There was no evidence of more generalised autonomic failure or neurological deficit. In two patients the condition appeared to be static and, according to the patients' accounts was life long. In the third the sweating loss was present for three years prior to pain loss becoming evident from C2/3 to T1 on the same side as the sweating loss. These patients, together with two recent case reports, indicate that isolated local autonomic failure, probably from a discrete cord lesion, can be a cause of presenting symptoms related to sweating loss or to change in temperature in a limb.
本文描述了三名主要表现为单肢自主神经功能衰竭的患者。生理学研究表明，受累肢体存在出汗减少，这似乎是由于节前自主神经病变，而非汗腺异常所致。所有三名患者均有血管运动控制功能障碍的证据。没有更广泛的自主神经功能衰竭或神经功能缺损的证据。两名患者的病情似乎静止不变，据患者自述，这种情况持续了一生。第三名患者在出汗减少的同一侧，从C2/3至T1出现疼痛之前，出汗减少已有三年。这些患者，连同最近的两份病例报告表明，孤立的局部自主神经功能衰竭，可能源于脊髓的离散性病变，可能是导致与出汗减少或肢体温度变化相关症状的原因。
