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一种新型的脱套法尿道成形术治疗轻度尿道下弯的尿道下裂:改良方法可完全切除尿道板下的瘢痕组织,并获得长期效果。

A novel onlay urethroplasty for hypospadias with mild chordee after degloving: modified for complete removal of scar tissue underlying the urethral plate and for long-term outcomes.

机构信息

Department of Urology, Children's Hospital of Nanjing Medical University, Jiangsu Provincial Children's Medical Center, Nanjing 210008, China.

出版信息

Asian J Androl. 2022 Nov-Dec;24(6):639-642. doi: 10.4103/aja202257.

DOI:10.4103/aja202257
PMID:36124533
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9809498/
Abstract

Urethral plate (UP)-preserving urethroplasty is simple and has few complications, but it may affect the development of penis in the long term and lead to recurrent chordee. In this study, we used obliquely cut UP to repair hypospadias with mild chordee after degloving (15°-30°) and compared the results with onlay urethroplasty to explore its rationality and feasibility. Between April 2018 and October 2020, 108 hypospadias patients underwent onlay urethroplasty or modified onlay urethroplasty. Clinical data were prospectively collected, and medium-term outcomes were assessed at follow-up. The complications were compared between the two groups. Forty-four patients underwent the modified onlay procedure (Group I), with follow-up time (mean ± standard deviation [s.d.]) of 23.2 ± 4.5 (range: 17-31) months. Sixty-four patients underwent a standard onlay procedure (Group II), with follow-up time (mean ± s.d.) of 39.7 ± 3.9 (range: 32-46) months. There was no difference in age at surgery. The urethral defect length and operative time were longer in Group I. Six cases of fistula and one case each of stricture and diverticulum were reported in Group I. In Group II, 11 cases of fistula and one case each of stricture and diverticulum were reported. The complication rates were 18.2% and 20.3% in Group I and Group II, respectively (P > 0.05). These medium-term follow-up results demonstrate that the modified onlay procedure (oblique cut UP urethroplasty) is a safe and feasible technique for hypospadias with mild chordee after degloving. Compared with standard onlay urethroplasty, this modified procedure is conducive to the complete removal of scar tissue underlying the UP without increasing the risk of surgical complications.

摘要

保留尿道板的尿道成形术操作简单,并发症少,但可能会影响阴茎的长期发育,导致尿道下裂复发。本研究采用斜切尿道板修复脱套后轻度尿道下弯(15°-30°)的尿道下裂,并与尿道板加盖术进行比较,探讨其合理性和可行性。2018 年 4 月至 2020 年 10 月,108 例尿道下裂患者接受了尿道板加盖术或改良尿道板加盖术。前瞻性收集临床资料,随访评估中期结果。比较两组患者的并发症。44 例患者接受改良尿道板加盖术(I 组),随访时间(均数±标准差)为 23.2±4.5(17-31)个月。64 例行标准尿道板加盖术(II 组),随访时间(均数±标准差)为 39.7±3.9(32-46)个月。两组患者的手术年龄差异无统计学意义。I 组患者的尿道缺损长度和手术时间较长。I 组 6 例出现瘘,1 例出现狭窄,1 例出现憩室。II 组中,11 例出现瘘,1 例出现狭窄,1 例出现憩室。I 组和 II 组的并发症发生率分别为 18.2%和 20.3%(P>0.05)。这些中期随访结果表明,对于脱套后轻度尿道下弯的尿道下裂,改良尿道板加盖术(斜切尿道板尿道成形术)是一种安全可行的技术。与标准尿道板加盖术相比,该改良术式有利于彻底切除尿道板下的瘢痕组织,而不会增加手术并发症的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e610/9809498/298c81792116/AJA-24-639-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e610/9809498/218db29459bc/AJA-24-639-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e610/9809498/298c81792116/AJA-24-639-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e610/9809498/218db29459bc/AJA-24-639-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e610/9809498/298c81792116/AJA-24-639-g002.jpg

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本文引用的文献

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Commentary: Recurrent chordee in 59 adolescents and young adults following childhood hypospadias repair.
J Pediatr Urol. 2020 Aug;16(4):521-522. doi: 10.1016/j.jpurol.2020.06.005. Epub 2020 Jun 20.
2
Recurrent chordee in 59 adolescents and young adults following childhood hypospadias repair.59例青少年及青年在儿童期尿道下裂修复术后出现复发性阴茎下弯。
J Pediatr Urol. 2020 Apr;16(2):162.e1-162.e5. doi: 10.1016/j.jpurol.2019.11.013. Epub 2019 Dec 2.
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Hypospadias repair with onlay preputial graft: a 25-year experience with long-term follow-up.采用包皮镶嵌移植术修复尿道下裂:25年长期随访经验
BJU Int. 2016 Sep;118(3):451-7. doi: 10.1111/bju.13419. Epub 2016 Feb 17.
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Transverse preputial onlay island flap urethroplasty for single-stage correction of proximal hypospadias.横行包皮岛状皮瓣尿道成形术用于一期矫正近端尿道下裂。
World J Urol. 2016 Jul;34(7):1019-24. doi: 10.1007/s00345-015-1686-1. Epub 2015 Sep 22.
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Meta-analysis of complication rates of the tubularized incised plate (TIP) repair.管状切开板(TIP)修复并发症发生率的荟萃分析。
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Population based nationwide study of hypospadias in Sweden, 1973 to 2009: incidence and risk factors.基于人群的瑞典 1973 年至 2009 年尿道下裂的全国性研究:发病率和危险因素。
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Urethral mobilization for distal and mid shaft hypospadias with chordee.尿道 mobilization 治疗伴有阴茎下弯的远端和中段尿道下裂。
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Characterization of the urethral plate and the underlying tissue defined by expression of collagen subtypes and microarchitecture in hypospadias.尿道下裂中尿道板及由胶原亚型表达和微观结构所定义的下层组织的特征分析。
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