Tamura Mitsuyoshi, Uzawa Akiyuki, Kitayama Yoshihisa, Habu Yuji, Kuwabara Satoshi
Department of Neurology, Chiba University Graduate School of Medicine, Chiba, JPN.
Department of Reproductive Medicine, Chiba University Graduate School of Medicine, Chiba, JPN.
Cureus. 2022 Aug 16;14(8):e28061. doi: 10.7759/cureus.28061. eCollection 2022 Aug.
We describe a 46-year-old woman who developed multiple cerebral infarctions in the left middle cerebral artery territory and deep vein thrombosis, presumably related to uterine adenomyosis. Uterine adenomyosis can cause coagulation abnormalities, as observed in Trousseau's syndrome. Along with previous reports, our case experienced a stroke during menstruation and presented with increased cancer antigen 125 (CA125) levels. A hysterectomy was performed to prevent the recurrence of cerebral infarction. Our case also had complicated deep vein thrombosis, which is also known as a complication of uterine adenomyosis. We consider cerebral infarction and deep vein thrombosis with uterine adenomyosis might be caused by a common mechanism, hypercoagulation. Hysterectomy requires careful discussion before undergoing it because of fertility problems, but it might be the most effective approach for preventing the recurrence of brain infarction derived from adenomyosis and may be effective for both cerebral infarction and deep vein thrombosis.
我们描述了一名46岁女性，她在左侧大脑中动脉区域发生多发性脑梗死，并伴有深静脉血栓形成，推测与子宫腺肌病有关。子宫腺肌病可导致凝血异常，如在特鲁索综合征中所见。与既往报道一致，我们的病例在月经期间发生中风，且癌抗原125（CA125）水平升高。为预防脑梗死复发，患者接受了子宫切除术。我们的病例还合并有深静脉血栓形成，这也是子宫腺肌病的一种并发症。我们认为子宫腺肌病合并脑梗死和深静脉血栓形成可能由共同机制——高凝状态引起。由于生育问题，在进行子宫切除术之前需要仔细讨论，但它可能是预防源自腺肌病的脑梗死复发的最有效方法，并且可能对脑梗死和深静脉血栓形成均有效。
