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双相情感障碍新出院患者近期躁狂症状的识别

Identifying Recent Manic Symptoms by Newly Discharged Patients with Bipolar Disorder.

作者信息

Alaei Solmaz, Jalali Nadoushan Amir Hossein, Soraya Shiva, Maraghi Elham, Shabani Amir

机构信息

Hamedan University of Medical Sciences, Hamedan, Iran.

Mental Health Research Center, Department of Psychiatry, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

出版信息

Med J Islam Repub Iran. 2022 Apr 19;36:38. doi: 10.47176/mjiri.36.38. eCollection 2022.

Abstract

Bipolar disorder type I is a chronic and recurrent disease and is considered as the ninth nonfatal disease. Identifying the symptoms of the manic episode, which are more likely detected by patients, increases the ability of psychiatrists in diagnosing this disorder. In this cross-sectional study, a total of 96 patients with bipolar disorder were enrolled from 2 academic psychiatric centers. Then, using the patients' medical records, demographic data were collected. Further, both the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) interview and the Young mania rating scale (Y-MRS) scale were also performed. Then, about 27 to 33 days after discharge, the patients were contacted by phone and the SCID-I interview was conducted again. Meanwhile, to make the patients focus on the period from which they have recently improved, the phrase "the recent period of hospitalization" was added to the interview questions and the symptoms were checked. At the beginning of the hospitalization, the most common symptom in the total population was irritable mood (89.5%): in the male population decreased need for sleep (98.2%), and in the female population irritable mood (97.5%). In addition, in the evaluation, about 1 month later, irritable mood (69.7%) and decreased need for sleep (67.7%) were the most common symptoms detected by the patients. In terms of the predictive value of each symptom to the diagnosis of that symptom by the psychiatrist, the highest positive predictive value was related to the symptoms of irritable mood (95.5%), decreased need for sleep (95.4%), and talkativeness (95.2%). However, the highest negative predictive value was related to the symptom of elevated mood (87.5%). The patients who have passed manic episodes are more able to detect some symptoms of this episode. Despite some limitations, it seems that using these statistical findings in practice may promote clinical assessment and diagnosis of bipolar disorder type I by psychiatrists.

摘要

I型双相情感障碍是一种慢性复发性疾病,被认为是第九大非致命性疾病。识别躁狂发作的症状(患者更有可能察觉到这些症状)可提高精神科医生诊断该疾病的能力。在这项横断面研究中,总共从2个学术性精神科中心招募了96例双相情感障碍患者。然后,利用患者的病历收集人口统计学数据。此外,还进行了《精神障碍诊断与统计手册》第四版轴I障碍的结构化临床访谈(SCID-I)和杨氏躁狂评定量表(Y-MRS)。然后,在出院后约27至33天,通过电话联系患者并再次进行SCID-I访谈。同时,为了让患者关注他们最近病情改善的时期,在访谈问题中添加了“近期住院期间”这一表述,并对症状进行检查。在住院初期,总体人群中最常见的症状是烦躁情绪(89.5%):男性人群中是睡眠需求减少(98.2%),女性人群中是烦躁情绪(97.5%)。此外,在大约1个月后的评估中,烦躁情绪(69.7%)和睡眠需求减少(67.7%)是患者察觉到的最常见症状。就每种症状对精神科医生诊断该症状的预测价值而言,最高的阳性预测价值与烦躁情绪(95.5%)、睡眠需求减少(95.4%)和健谈(95.2%)的症状相关。然而,最高的阴性预测价值与情绪高涨症状(87.5%)相关。经历过躁狂发作的患者更能察觉到该发作的一些症状。尽管存在一些局限性,但在实践中运用这些统计结果似乎可能促进精神科医生对I型双相情感障碍的临床评估和诊断。

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本文引用的文献

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Only half of bipolar I and II patients report prodromal symptoms.仅有一半的双相I型和II型患者报告有前驱症状。
J Affect Disord. 2008 Dec;111(2-3):366-71. doi: 10.1016/j.jad.2008.03.011. Epub 2008 Apr 28.
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A systematic review of manic and depressive prodromes.躁狂和抑郁前驱症状的系统评价。
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