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改良版分裂情感性障碍轻躁狂模块(SCID-Hba):一项详细的系统现象学探究。

The modified SCID Hypomania Module (SCID-Hba): a detailed systematic phenomenologic probing.

作者信息

Benazzi Franco, Akiskal Hagop S

机构信息

Hecker Psychiatry Research Center, Forli, Italy.

出版信息

J Affect Disord. 2009 Oct;117(3):131-6. doi: 10.1016/j.jad.2009.06.001. Epub 2009 Jun 23.

Abstract

Diagnosing past hypomania is a difficult task. Current structured interviews (e.g. CIDI, SCID) limit the ability to probe for hypomania. A modified SCID Hypomania Module was published by us (Benazzi and Akiskal, J Affect Disord 2003; Akiskal and Benazzi, J Clin Psychiatry 2005) in order to overcome the limitations of structured interviewing. Our papers outlined the framework of the modified SCID. In response to requests from many readers of this journal and other clinicians and investigators, we are hereby providing a more explicit step-by-step phenomenologic probing interview. DSM-IV criteria have to be met, but the probing for hypomania is very different from that of the SCID. All past hypomanic symptoms are assessed. No negative meaning is given to symptoms, as hypomania often improves functioning and it is seen by patients as a state of well being. The first step is probing for overactivity (increase in goal-directed activity), because observable behaviors are easier to remember by patients and key informants. There is no gold-standard for overactivity: each person becomes his/her own standard to 'measure' a clear-cut departure form the usual behavior. Questions, correspondingly, can change from patient to patient. The emotions associated with behavioral change are easier to be remembered than asking them first, as in the structured interviews. Structured interviews have mood change (elation, irritability) as stem question (corresponding to the criterion A of DSM-IV, which postulates that it must always be present). However, apart from a likely recall bias of past emotions, the description of mood change appears more or less negative in structured interviews (to increase specificity but by much reducing sensitivity, i.e. the false-negatives). Presenting mood change as simply having been more elated/irritable than usual can easily be interpreted as normal mood fluctuations, while presenting mood change as much more than usual could be understood as a severe mental disorder. Both ways are likely to lead to a negative response, moving the interviewers to unipolar disorders (the skip-out instruction). Our modified SCID is a fully semi-structured interview: many questions are asked about each symptom to make the question understandable according to each patient, and, very importantly, examples of the 'events' are systematically asked to check understanding and clinical relevance. Our interview follows DSM-IV criteria (apart from the minimum duration, 2 days versus DSM-IV 4 days), i.e. mood change must always been present, but our probing detects more hypomanic episodes than the SCID.

摘要

诊断过去的轻躁狂发作是一项艰巨的任务。目前的结构化访谈(如复合性国际诊断交谈检查表、精神障碍诊断与统计手册结构性临床访谈)限制了对轻躁狂发作进行深入探究的能力。为了克服结构化访谈的局限性,我们(贝纳齐和阿基斯卡尔,《情感障碍杂志》2003年;阿基斯卡尔和贝纳齐,《临床精神病学杂志》2005年)发表了一个改良的精神障碍诊断与统计手册结构性临床访谈轻躁狂发作模块。我们的论文概述了改良的精神障碍诊断与统计手册结构性临床访谈的框架。应本杂志众多读者以及其他临床医生和研究人员的要求,我们在此提供一个更明确的逐一步骤的现象学探究访谈。必须符合《精神疾病诊断与统计手册》第四版的标准,但对轻躁狂发作的探究与精神障碍诊断与统计手册结构性临床访谈有很大不同。要评估所有过去的轻躁狂症状。不对症状赋予负面意义,因为轻躁狂发作往往会改善功能,患者将其视为一种良好状态。第一步是探究活动过度(目标导向活动增加),因为可观察到的行为更容易被患者和关键信息提供者记住。对于活动过度没有金标准:每个人都成为自己的标准来“衡量”与平常行为的明显偏离。相应地,问题会因患者而异。与行为变化相关的情绪比像结构化访谈那样先询问情绪更容易被记住。结构化访谈将情绪变化(欣快、易怒)作为起始问题(对应于《精神疾病诊断与统计手册》第四版的A标准,该标准假定情绪变化必须始终存在)。然而,除了过去情绪可能存在的回忆偏差外,在结构化访谈中对情绪变化的描述或多或少是负面的(为了提高特异性,但大大降低了敏感性,即假阴性)。将情绪变化简单描述为比平常更欣快/易怒很容易被解释为正常的情绪波动,而将情绪变化描述为比平常强烈得多可能会被理解为严重的精神障碍。这两种方式都可能导致负面反应,使访谈者转向单相障碍(跳转到单相障碍的指令)。我们改良的精神障碍诊断与统计手册结构性临床访谈是一种完全半结构化访谈:针对每个症状会问很多问题,以便根据每个患者的情况使问题易于理解,而且非常重要的是,会系统地询问“事件”的例子以检查理解情况和临床相关性。我们的访谈遵循《精神疾病诊断与统计手册》第四版的标准(除了最短持续时间,《精神疾病诊断与统计手册》第四版要求4天,我们要求2天),即情绪变化必须始终存在,但我们的探究能检测到比精神障碍诊断与统计手册结构性临床访谈更多的轻躁狂发作。

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