Carmona Adrien, Marchandot Benjamin, Sagnard Mylene, Morel Olivier
Division of Cardiovascular Medicine, Nouvel Hopital Civil, Strasbourg University Hospital, 1 place de l'Hôpital, 67000 Strasbourg, France.
Division of Nephrology Critical Care and Transplant Nephrology, Nouvel Hopital Civil, Strasbourg University Hospital, 1 place de l'Hôpital, 67000 Strasbourg, France.
Eur Heart J Case Rep. 2022 Sep 3;6(9):ytac367. doi: 10.1093/ehjcr/ytac367. eCollection 2022 Sep.
Myocardial infarction on non-occluded coronary artery represents a very specific subset of acute coronary syndrome (ACS). Coronary subclavian steal syndrome (CSSS) is defined by a left subclavian artery stenosis in case of (i) left internal mammary artery (LIMA) used to bypass left anterior descending artery (LAD) and (ii) >75% stenosis of the left subclavian artery prior to the origin of the LIMA to LAD graft. Here we report the case of a CSSS causing ACS.
A 71-year-old man with history of LIMA to LAD coronary artery bypass surgery was admitted to the nephrology intensive care unit for acute kidney injury requiring dialysis. Due to rapid deterioration, altered left ventricular ejection fraction and elevated -troponin levels, an urgent coronary angiography was performed. It revealed a subtotal occlusion of the left subclavian artery prior to the origin of the LIMA to LAD graft. This was responsible for a severely altered coronary flow in the LIMA and LAD. Revascularization of the proximal left subclavian artery with a stent was performed, enabling instant recovery of distal coronary flows.
ACS due to CSSS in this report highlights the complexity of the cardio-renal interaction. Patients with coronary artery bypass graft and chronic kidney disease commonly exhibit a higher risk for severe progression of atherosclerosis at multiple sites. CSSS treatments include secondary prevention measures and revascularization (if indicated) such as an endovascular approach.
非闭塞性冠状动脉心肌梗死是急性冠状动脉综合征(ACS)中一个非常特殊的亚型。冠状动脉锁骨下动脉窃血综合征(CSSS)的定义为:(i)左乳内动脉(LIMA)用于旁路移植左前降支动脉(LAD),且(ii)在LIMA至LAD移植起点之前左锁骨下动脉狭窄>75%。在此我们报告一例由CSSS导致ACS的病例。
一名有LIMA至LAD冠状动脉旁路移植手术史的71岁男性因急性肾损伤需要透析而入住肾病重症监护病房。由于病情迅速恶化、左心室射血分数改变及肌钙蛋白水平升高,遂进行了紧急冠状动脉造影。结果显示在LIMA至LAD移植起点之前左锁骨下动脉几乎完全闭塞。这导致了LIMA和LAD中冠状动脉血流严重改变。对左锁骨下动脉近端进行了支架血管重建,使冠状动脉远端血流立即恢复。
本报告中由CSSS导致的ACS突出了心肾相互作用的复杂性。接受冠状动脉旁路移植术和患有慢性肾病的患者通常在多个部位发生动脉粥样硬化严重进展的风险更高。CSSS的治疗包括二级预防措施和血管重建(如适用),例如血管内介入治疗。