Circulation. 2019 Apr 30;139(18):e891-e908. doi: 10.1161/CIR.0000000000000670.
Myocardial infarction in the absence of obstructive coronary artery disease is found in ≈5% to 6% of all patients with acute infarction who are referred for coronary angiography. There are a variety of causes that can result in this clinical condition. As such, it is important that patients are appropriately diagnosed and an evaluation to uncover the correct cause is performed so that, when possible, specific therapies to treat the underlying cause can be prescribed. This statement provides a formal and updated definition for the broadly labelled term MINOCA (incorporating the definition of acute myocardial infarction from the newly released "Fourth Universal Definition of Myocardial Infarction") and provides a clinically useful framework and algorithms for the diagnostic evaluation and management of patients with myocardial infarction in the absence of obstructive coronary artery disease.
在所有接受冠状动脉造影检查的急性心肌梗死患者中，约有 5%至 6%存在无阻塞性冠状动脉疾病的心肌梗死。有多种原因可导致这种临床情况。因此，重要的是对患者进行适当的诊断，并进行评估以找出正确的病因，以便在可能的情况下，开出针对潜在病因的特定治疗方法。本声明为广义上的 MINOCA 术语（包含新发布的“第四次心肌梗死通用定义”中的急性心肌梗死定义）提供了正式和更新的定义，并为无阻塞性冠状动脉疾病的心肌梗死患者的诊断评估和管理提供了一个临床有用的框架和算法。
