Pediatric Pain Research Center, Cincinnati Children's Hospital, Cincinnati, OH, USA.
Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital, Cincinnati, OH, USA.
Scand J Pain. 2022 Sep 22;22(4):679-680. doi: 10.1515/sjpain-2022-0097. Print 2022 Oct 26.
Our current understanding of central nervous system mechanisms supporting the experience of pain remains remarkably limited and produces substantial challenges when seeking to better diagnose and treat chronic pain. A new conceptual framework - The Distributed Nociceptive System - emphasizes system-level aspects of nociceptive processing by incorporating population coding and distributed process. The Distributed Nociceptive System provides a structure for understanding complex spatial aspects of chronic pain and provides a clear rationale for the further development of multi-disciplinary treatments for chronic pain.
我们目前对支持疼痛体验的中枢神经系统机制的理解仍然非常有限,这在寻求更好地诊断和治疗慢性疼痛时带来了巨大的挑战。一个新的概念框架——分布式伤害感受系统——通过纳入群体编码和分布式处理,强调了伤害感受处理的系统层面。分布式伤害感受系统为理解慢性疼痛的复杂空间方面提供了一个结构,并为慢性疼痛的多学科治疗的进一步发展提供了明确的理由。