Am J Nurs. 2022 Oct 1;122(10):59. doi: 10.1097/01.NAJ.0000890244.62778.a4.
According to this study: In a phase 2/phase 3 study of Paxlovid use in patients at standard risk for developing severe COVID-19, the primary end point of self-reported sustained alleviation of all symptoms for four consecutive days wasn't met.A nonsignificant risk reduction in hospitalizations and death was seen in a subgroup of patients who had at least one risk factor for severe COVID-19.
在一项针对有发展为重症 COVID-19 标准风险的患者使用 Paxlovid 的 2/3 期研究中,主要终点为自我报告的所有症状连续四天持续缓解并未达到。在至少有一个重症 COVID-19 风险因素的患者亚组中,住院和死亡的风险降低没有统计学意义。