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沙特阿拉伯抗生素耐药菌频率的系统评价与荟萃分析

Systematic Review and Meta-Analysis on the Frequency of Antibiotic-Resistant Species in Saudi Arabia.

作者信息

Banawas Saeed S

机构信息

Department of Medical Laboratories, College of Applied Medical Science, Majmaah University, Al-Majmaah 11952, Saudi Arabia.

Health and Basic Sciences Research Center, Majmaah University, Al-Majmaah 11952, Saudi Arabia.

出版信息

Antibiotics (Basel). 2022 Aug 29;11(9):1165. doi: 10.3390/antibiotics11091165.

DOI:10.3390/antibiotics11091165
PMID:36139945
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9495114/
Abstract

is a genus comprising Gram-positive, rod-shaped, spore-forming, anaerobic bacteria that cause a variety of diseases. However, there is a shortage of information regarding antibiotic resistance in the genus in Saudi Arabia. This comprehensive analysis of research results published up until December 2021 intends to highlight the incidence of antibiotic resistance in species in Saudi Arabia. PubMed, Google Scholar, Web of Science, SDL, and ScienceDirect databases were searched using specific keywords, and ten publications on antibiotic resistance in species in Saudi Arabia were identified. We found that the rates of resistance of to antibiotics were as follows: 42% for ciprofloxacin, 83% for gentamicin, 28% for clindamycin, 25% for penicillin, 100% for levofloxacin, 24% for tetracycline, 77% for nalidixic acid, 50% for erythromycin, 72% for ampicillin, and 28% for moxifloxacin; whereas those of were: 21% for metronidazole, 83% for ceftiofur, 39% for clindamycin, 59% for penicillin, 62% for erythromycin, 47% for oxytetracycline, and 47% for lincomycin. The current findings suggest that ceftiofur, erythromycin, lincomycin, and oxytetracycline should not be used in infection treatments in humans or animals in Saudi Arabia.

摘要

是一个属,包含革兰氏阳性、杆状、形成孢子的厌氧细菌,可导致多种疾病。然而,沙特阿拉伯关于该属抗生素耐药性的信息匮乏。这项对截至2021年12月发表的研究结果的综合分析旨在突出沙特阿拉伯该属物种中抗生素耐药性的发生率。使用特定关键词搜索了PubMed、谷歌学术、科学网、SDL和科学Direct数据库,确定了十篇关于沙特阿拉伯该属物种抗生素耐药性的出版物。我们发现,该属对各类抗生素的耐药率如下:环丙沙星为42%,庆大霉素为83%,克林霉素为28%,青霉素为25%,左氧氟沙星为100%,四环素为24%,萘啶酸为77%,红霉素为50%,氨苄西林为72%,莫西沙星为28%;而另一属的耐药率为:甲硝唑为21%,头孢噻呋为83%,克林霉素为39%,青霉素为59%,红霉素为62%,土霉素为47%,林可霉素为47%。目前的研究结果表明,在沙特阿拉伯,头孢噻呋、红霉素、林可霉素和土霉素不应用于人类或动物的该属感染治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b95/9495114/ce808df3f4a9/antibiotics-11-01165-g002a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b95/9495114/fdb81c80f3aa/antibiotics-11-01165-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b95/9495114/ce808df3f4a9/antibiotics-11-01165-g002a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b95/9495114/fdb81c80f3aa/antibiotics-11-01165-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b95/9495114/ce808df3f4a9/antibiotics-11-01165-g002a.jpg

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