Chandra B
Eur Neurol. 1978;17(5):265-70. doi: 10.1159/000114956.
Results are reported of a double-blind trial with L-dopa in 39 patients with measles encephalitis. In this treatment series, L-dopa improved the state of awareness and the diffuse disturbances in the EEG. There was a significant difference too, regarding the outcome between patients treated with L-dopa and placebo. The death rate in the L-dopa-treated group was lower and there were fewer mental sequelae. It is suggested, that L-dopa should be used in patients with measles encephalitis.
报告了一项针对39例麻疹脑炎患者使用左旋多巴的双盲试验结果。在这个治疗系列中,左旋多巴改善了意识状态和脑电图中的弥漫性紊乱。在使用左旋多巴和安慰剂治疗的患者之间,结果也存在显著差异。左旋多巴治疗组的死亡率较低,精神后遗症也较少。建议在麻疹脑炎患者中使用左旋多巴。