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会厌固定术是治疗会厌塌陷引起的阻塞性睡眠呼吸暂停的首选治疗方法。

Epiglottopexy Is a Treatment of Choice for Obstructive Sleep Apnea Caused by a Collapsing Epiglottis.

作者信息

Masárová Michaela, Formánek Martin, Jor Ondřej, Novák Vilém, Vrtková Adéla, Matoušek Petr, Komínek Pavel, Zeleník Karol

机构信息

Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Ostrava, 708 52 Ostrava, Czech Republic.

Faculty of Medicine, University of Ostrava, 708 52 Ostrava, Czech Republic.

出版信息

Life (Basel). 2022 Sep 5;12(9):1378. doi: 10.3390/life12091378.

Abstract

Drug-induced sleep endoscopy (DISE) reveals epiglottic collapse to be a frequent cause of obstructive sleep apnea (OSA) and intolerance of positive airway pressure (PAP). These patients require different management. This prospective study aimed to compare transoral laser epiglottopexy outcomes in patients with OSA caused by epiglottic collapse with the patients’ previous PAP outcomes. Fifteen consecutive adult patients with OSA and epiglottic collapse during DISE were included; ten were analyzed. Before inclusion, PAP was indicated and ineffective in six patients, one of whom underwent unsuccessful uvulopalatopharyngoplasty. PAP was performed during DISE in all patients before epiglottopexy and was uniformly ineffective. ENT control was performed at 1 week and 1 month, and control limited polygraphy to 6 months after surgery. The apnea−hypopnea index (AHI) and Epworth Sleepiness Scale (ESS) were significantly improved (p < 0.001 and p = 0.003, respectively) in all patients after epiglottopexy. Surgery was successful in 9/10 patients; the remaining patient had a significantly decreased AHI and could finally tolerate PAP. Transoral laser epiglottopexy is used to treat OSA in patients with epiglottic collapse. Unlike other methods, it significantly reduces both AHI and ESS and should be considered for these patients. An active search for OSA patients with epiglottic collapse is recommended to prevent treatment failure.

摘要

药物诱导睡眠内镜检查(DISE)显示会厌塌陷是阻塞性睡眠呼吸暂停(OSA)和气道正压通气(PAP)不耐受的常见原因。这些患者需要不同的治疗方法。这项前瞻性研究旨在比较会厌塌陷导致的OSA患者经口激光会厌固定术的治疗效果与患者之前使用PAP的治疗效果。纳入了15例在DISE期间出现OSA与会厌塌陷的成年患者;对其中10例进行了分析。纳入研究前,6例患者被建议使用PAP但效果不佳,其中1例患者接受悬雍垂腭咽成形术未成功。所有患者在会厌固定术前的DISE期间均进行了PAP治疗,且均无效。术后1周和1个月进行耳鼻喉科检查,术后6个月进行有限的多导睡眠图检查。所有患者在会厌固定术后,呼吸暂停低通气指数(AHI)和爱泼华嗜睡量表(ESS)均有显著改善(分别为p < 0.001和p = 0.003)。10例患者中有9例手术成功;其余1例患者的AHI显著降低,最终能够耐受PAP。经口激光会厌固定术用于治疗会厌塌陷导致的OSA患者。与其他方法不同,它能显著降低AHI和ESS,对于这些患者应考虑采用该方法。建议积极筛查会厌塌陷的OSA患者,以防止治疗失败。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cccf/9502758/376eadcd27f4/life-12-01378-g001.jpg

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