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会厌固定术联合或不联合杓会厌皱劈裂术治疗小儿阻塞性睡眠呼吸暂停的疗效比较

Epiglottopexy with or without aryepiglottic fold division: Comparing outcomes in the treatment of pediatric obstructive sleep apnea.

机构信息

West Virginia University, Department of Otolaryngology, Head and Neck Surgery, United States of America.

West Virginia University, Department of Otolaryngology, Head and Neck Surgery, United States of America.

出版信息

Am J Otolaryngol. 2020 Jul-Aug;41(4):102478. doi: 10.1016/j.amjoto.2020.102478. Epub 2020 Apr 4.

DOI:10.1016/j.amjoto.2020.102478
PMID:32303392
Abstract

OBJECTIVE

To determine the success of epiglottopexy with or without aryepiglottic fold division for treatment of patients with obstructive sleep apnea (OSA) with epiglottic obstruction.

STUDY DESIGN

Retrospective chart review.

SETTING

Tertiary care academic hospital.

METHODS

Children with sleep study proven OSA who underwent epiglottopexy with or without aryepiglottic fold division from January 2013 to June 2017 were included. The epiglottis contributed to airway obstruction in all patients. Pre- and post-operative apnea-hypopnea index (AHI) were compared. Age, sex, body mass index (BMI) z-score and post-operative complications were also evaluated. Success was defined by post-operative AHI < 5.0 with resolution of OSA symptoms or AHI ≤ 1.0 events per hour.

RESULTS

Twenty-eight children (age 2-17 years) underwent either epiglottopexy with division of aryepiglottic folds (N = 18) or epiglottopexy alone (N = 10). There was no difference in preoperative age, AHI, or BMI between the groups. Post-operative AHI was lower in the group undergoing epiglottopexy alone (AHI 1.50) versus with aryepiglottic fold division (AHI 3.17) (P < 0.05). No difference was found in mean AHI improvement between the two groups. For the entire cohort, success criteria were met by 53.6% of patients for AHI < 5.0 without symptoms and 25.0% of patients for AHI ≤ 1.0, with no difference in surgical success between procedures (P > 0.05).

CONCLUSIONS

Children undergoing epiglottopexy with division of aryepiglottic folds for laryngeal collapse were as likely to have improved OSA symptoms as children undergoing epiglottopexy alone.

摘要

目的

探讨会厌固定术联合或不联合杓会厌皱劈裂术治疗会厌阻塞型阻塞性睡眠呼吸暂停(OSA)的疗效。

研究设计

回顾性病例分析。

设置

三级学术医院。

方法

纳入 2013 年 1 月至 2017 年 6 月间因睡眠研究证实 OSA 而行会厌固定术联合或不联合杓会厌皱劈裂术的患儿。所有患者的气道阻塞均由会厌引起。比较术前和术后的呼吸暂停低通气指数(AHI)。还评估了年龄、性别、体重指数(BMI)Z 评分和术后并发症。术后 AHI<5.0 且 OSA 症状缓解或 AHI 每小时≤1.0 事件定义为成功。

结果

28 例患儿(年龄 2-17 岁)行会厌固定术联合杓会厌皱劈裂术(N=18)或单纯会厌固定术(N=10)。两组患儿术前年龄、AHI 或 BMI 无差异。单纯会厌固定术组术后 AHI 低于联合杓会厌皱劈裂术组(AHI 1.50 比 AHI 3.17)(P<0.05)。两组间 AHI 改善的平均差异无统计学意义。对于整个队列,53.6%的患者满足 AHI<5.0 且无症状,25.0%的患者满足 AHI≤1.0 的标准,两种手术方法的手术成功率无差异(P>0.05)。

结论

对于因喉塌陷而行会厌固定术联合杓会厌皱劈裂术的患儿,其 OSA 症状的改善与单纯行会厌固定术的患儿相似。

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