Departamento de Química Inorgánica, Orgánica y Bioquímica-Centro de Innovación en Química Avanzada (ORFEO-CINQA), Facultad de Ciencias y Tecnologías Químicas, Universidad de Castilla-La Mancha, 13071 Ciudad Real, Spain.
Molecules. 2022 Sep 13;27(18):5962. doi: 10.3390/molecules27185962.
For decades, ligands such as phosphanes or cyclopentadienyl ring derivatives have dominated Coordination and Organometallic Chemistry. At the same time, alternative compounds have emerged that could compete either for a more practical and accessible synthesis or for greater control of steric and electronic properties. Guanidines, nitrogen-rich compounds, appear as one such potential alternatives as ligands or proligands. In addition to occurring in a plethora of natural compounds, and thus in compounds of pharmacological use, guanidines allow a wide variety of coordination modes to different metal centers along the periodic table, with their monoanionic chelate derivatives being the most common. In this review, we focused on the organometallic chemistry of guanidinato compounds, discussing selected examples of coordination modes, reactivity and uses in catalysis or materials science. We believe that these amazing ligands offer a new promise in Organometallic Chemistry.
几十年来，膦类或环戊二烯基环衍生物等配体一直主导着配位和金属有机化学。与此同时，也出现了一些替代化合物，它们要么在更实际和更易获得的合成方面具有竞争力，要么在控制空间和电子性质方面具有竞争力。胍类化合物，作为一种富氮化合物，作为配体或前配体，似乎是一种潜在的替代品。除了在大量的天然化合物中存在，因此也存在于具有药理用途的化合物中，胍类化合物允许在元素周期表上的不同金属中心采用多种配位模式，其单价螯合衍生物是最常见的。在这篇综述中，我们专注于胍化合物的金属有机化学，讨论了配位模式、反应性和在催化或材料科学中的应用的一些实例。我们相信，这些令人惊叹的配体在金属有机化学中提供了新的前景。
