Cutaneous and lip squamous cell carcinomas in an albinism patient: A case report.

INTRODUCTION AND IMPORTANCE

The incidence of squamous cell carcinoma (SCC) in the population aged under 30 years reaches only 1% of total cases. We report the first case from Papua, Indonesia, with a double primary SCC in a patient aged just 25 years, with albinism as a risk factor. This case report can hopefully enrich existing knowledge of such tumors.

CASE PRESENTATION

A 25-year-old Papuan female patient came to the oncology clinic of Jayapura Regional General Hospital with a tumor on the left lower lip and a skin tumor on the right temporal side of the face. The patient noticed that the tumor on the lower lip appeared a few weeks earlier than that on the right temporal skin. Both tumors had grown gradually for 5 years. Both tumors were painless, but for the last 3 months, the tumor had bled easily. The patient was born with oculocutaneous albinism (OCA) without other syndromic or systemic disorders.

CLINICAL DISCUSSION AND CONCLUSION

In this patient, we suspected double primary SCCs considering the location of the tumor, which theoretically spreads distantly; the size of the lesion at less than 2 cm; the depth of the lesion at less than 4 mm; and the well-differentiated cytology. Another consideration was that patients with OCA have a 1000-fold risk of developing skin cancer and an increased risk of recurrence. Therefore, continual evaluation and screening are necessary.