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福克纳治疗疣的针刺技术:最小投入,最大收益。

Falkner's needling technique for the treatment of warts: Minimum investment, maximum benefit.

作者信息

Baveja Sukriti, Bhatt Siddharth, Vashisht Surbhi, Vashisht Deepak, Joshi Rajneesh, Pathania Vikas, Venugopal Ruby

机构信息

Professor (Dermatology), Command Hospital (Southern Command), Pune, India.

Resident (Dermatology), Command Hospital (Southern Command), Pune, India.

出版信息

Med J Armed Forces India. 2022 Sep;78(Suppl 1):S75-S81. doi: 10.1016/j.mjafi.2020.07.009. Epub 2020 Oct 9.

DOI:10.1016/j.mjafi.2020.07.009
PMID:36147396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9485768/
Abstract

BACKGROUND

Verruca vulgaris is a viral infection with high recurrence rates and is very difficult to treat. It occurs due to the ability of the virus to evade immune recognition. This immune evasion by the human papillomavirus (HPV) can be circumvented by injecting HPV antigens subcutaneously and inducing inflammation and a systemic immune response. Falkner technique is an approved technique for the treatment of warts. In this observational study, we analyzed the recovery rate among patients undergoing this technique as part of their routine treatment. The aim of this study is to study the clinical outcome of Falkner's needling technique that is being used for the treatment of verruca vulgaris.

METHODS

Under local anaesthesia, only a single wart was vertically punctured using a 26-gauge needle up till the subcutis multiple times till bleeding was observed. No treatment was done for other warts. Patients were advised not to take any anti-inflammatory medications for pain and were observed for responses after 1 week as well as 1 and 3 months.

RESULTS

Of 41 patients included in this study, the total resolution of both the punctured and distant warts occurred in 28 patients (68.29%) and partial response in 7 patients (17.1%) by the end of 3 months. Interestingly, individual warts that were subjected to needling showed complete resolution in 35 patients (85.4%).

CONCLUSION

Falkner's needling method provides a high rate of complete resolution of multiple warts at both the needled and distant sites after a single treatment session of only a single lesion. This modality has a high cure rate, is easy to perform, requires minimal infrastructure support, is cost-effective, and can be undertaken at most peripheral settings with minimal training.

摘要

背景

寻常疣是一种病毒感染,复发率高且极难治疗。其发生是由于病毒具有逃避免疫识别的能力。通过皮下注射人乳头瘤病毒(HPV)抗原并引发炎症和全身免疫反应,可以规避人乳头瘤病毒(HPV)的这种免疫逃逸。福克纳技术是一种经批准用于治疗疣的技术。在这项观察性研究中,我们分析了接受该技术作为常规治疗一部分的患者的治愈率。本研究的目的是探讨用于治疗寻常疣的福克纳针刺技术的临床疗效。

方法

在局部麻醉下,仅使用26号针头对单个疣体垂直穿刺直至皮下多次,直至观察到出血。其他疣体不进行治疗。建议患者不要服用任何止痛抗炎药物,并在1周以及1个月和3个月后观察反应。

结果

在本研究纳入的41例患者中,到3个月末,穿刺疣体和远处疣体完全消退的有28例(68.29%),部分缓解的有7例(17.1%)。有趣的是,接受针刺的单个疣体在35例患者(85.4%)中完全消退。

结论

福克纳针刺法在仅对单个病灶进行单次治疗后,能使针刺部位和远处的多个疣体实现高比例的完全消退。这种治疗方式治愈率高、操作简便、所需基础设施支持最少、性价比高,并且在大多数基层医疗单位经过最少培训即可开展。

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本文引用的文献

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Falknor's needling method as a potential immunotherapy in palmo-plantar warts.作为一种潜在的免疫疗法,Falknor 的针刺法治疗掌跖疣。
Indian J Dermatol Venereol Leprol. 2019 Jan-Feb;85(1):129. doi: 10.4103/ijdvl.IJDVL_809_17.
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Needling warts: are we any further forward?针刺治疗疣:我们有进展吗?
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Evolving role of immunotherapy in the treatment of refractory warts.免疫疗法在难治性疣治疗中的作用演变
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The Treatment of Verrucae Pedis Using Falknor's Needling Method: A Review of 46 Cases.使用福尔克诺针刺法治疗足疣:46例病例回顾
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