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被假性定位运动性癫痫掩盖的急性缺血性卒中表现:临床病例系列

Acute Ischemic Stroke Presentation Masked by Falsely Localizing Motor Seizure: A Clinical Case Series.

作者信息

Weil Erika L, Stitt Derek W, Rabinstein Alejandro A, Cascino Gregory D, Nasr Deena M

机构信息

Department of Neurology, Mayo Clinic, Rochester, MN, USA.

出版信息

Neurohospitalist. 2022 Oct;12(4):647-650. doi: 10.1177/19418744221108555. Epub 2022 Jun 14.

Abstract

In this case series, we describe a novel observation in which 4 patients with acute ischemic stroke secondary to large vessel occlusion and no history of seizure present with focal seizure activity localizable to a chronic, contralateral infarct. The explanation for this phenomenon is unknown but may be due to a combination of effects involving disrupted interhemispheric inhibitory connections and epileptogenic changes involving chronically infarcted tissue.

摘要

在这个病例系列中,我们描述了一种新的观察结果,即4例继发于大血管闭塞且无癫痫病史的急性缺血性卒中患者出现局灶性癫痫活动,可定位于慢性对侧梗死灶。这种现象的原因尚不清楚,但可能是由于涉及半球间抑制性连接中断和慢性梗死组织的致痫性改变等多种效应的综合作用。

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1
Long-term neurological, vascular, and mortality outcomes after stroke.卒中后的长期神经、血管和死亡率结局。
Int J Stroke. 2018 Oct;13(8):787-796. doi: 10.1177/1747493018798526. Epub 2018 Aug 30.
2
Defective interhemispheric inhibition in drug-treated focal epilepsies.药物治疗的局灶性癫痫中存在半球间抑制缺陷。
Brain Stimul. 2017 May-Jun;10(3):579-587. doi: 10.1016/j.brs.2016.12.002. Epub 2016 Dec 9.
3
Development of epilepsy after ischaemic stroke.缺血性卒中后癫痫的发生。
Lancet Neurol. 2016 Feb;15(2):185-197. doi: 10.1016/S1474-4422(15)00248-3. Epub 2015 Nov 17.
5
Recommendation for a definition of acute symptomatic seizure.急性症状性癫痫发作的定义推荐。
Epilepsia. 2010 Apr;51(4):671-5. doi: 10.1111/j.1528-1167.2009.02285.x. Epub 2009 Sep 3.
8
Seizures and epilepsy after ischemic stroke.缺血性中风后的癫痫发作与癫痫
Stroke. 2004 Jul;35(7):1769-75. doi: 10.1161/01.STR.0000130989.17100.96. Epub 2004 May 27.
9
Poststroke seizures.中风后癫痫发作。
Arch Neurol. 2002 Feb;59(2):195-201. doi: 10.1001/archneur.59.2.195.

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