Weil Erika L, Stitt Derek W, Rabinstein Alejandro A, Cascino Gregory D, Nasr Deena M
Department of Neurology, Mayo Clinic, Rochester, MN, USA.
Neurohospitalist. 2022 Oct;12(4):647-650. doi: 10.1177/19418744221108555. Epub 2022 Jun 14.
In this case series, we describe a novel observation in which 4 patients with acute ischemic stroke secondary to large vessel occlusion and no history of seizure present with focal seizure activity localizable to a chronic, contralateral infarct. The explanation for this phenomenon is unknown but may be due to a combination of effects involving disrupted interhemispheric inhibitory connections and epileptogenic changes involving chronically infarcted tissue.
在这个病例系列中,我们描述了一种新的观察结果,即4例继发于大血管闭塞且无癫痫病史的急性缺血性卒中患者出现局灶性癫痫活动,可定位于慢性对侧梗死灶。这种现象的原因尚不清楚,但可能是由于涉及半球间抑制性连接中断和慢性梗死组织的致痫性改变等多种效应的综合作用。