Lipina I G, Evtushenko Z S, Gnezdilova S M
Ontogenez. 1987 May-Jun;18(3):269-76.
The ovaries were studied in the sea urchins kept in a sea water added with 1, 50 and 100 micrograms/l cadmium chloride for 5, 15, 40, 72 and 130 days. The gland reaction depended on the drug dose and exposure. A short exposure (5 and 15 days) stimulated the development of a larger, as compared with the control, number of oogonia and raised the activity of acid and alkaline phosphatases. A long exposure decreased the number of germ cells, decelerated their growth, destroyed gametes and accessory cells, inhibited the activity of alkaline phosphatase. The cadmium accumulation in the ovaries was noted only on the 130th day at concentrations of 50 and 100 micrograms/l. The monitoring of morphological and biochemical indices allowed to conclude that cadmium exerted a toxic effect on the sea urchin ovaries.
对置于添加了1微克/升、50微克/升和100微克/升氯化镉的海水中5天、15天、40天、72天和130天的海胆卵巢进行了研究。腺体反应取决于药物剂量和暴露时间。与对照组相比，短时间暴露（5天和15天）刺激了更多卵原细胞的发育，并提高了酸性和碱性磷酸酶的活性。长时间暴露会减少生殖细胞数量，减缓其生长，破坏配子和辅助细胞，抑制碱性磷酸酶的活性。仅在第130天，当浓度为50微克/升和100微克/升时，才观察到卵巢中有镉积累。对形态学和生化指标的监测表明，镉对海胆卵巢产生了毒性作用。
