El Paso County Public Health, Colorado Springs, Colorado, USA.
Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Foodborne Pathog Dis. 2022 Oct;19(10):713-715. doi: 10.1089/fpd.2022.0038. Epub 2022 Sep 23.
During September 2019, public health authorities in El Paso County, Colorado, were notified of four patients who had presented to nearby hospitals with clinical features consistent with botulism, a paralytic illness caused by botulinum neurotoxin. One patient died soon after presentation; the other three patients required intensive care but recovered after receiving botulism antitoxin. Botulinum toxin type A was detected in serum from all patients. On further investigation, all four patients had shared a meal that included commercially prepared roasted potatoes from an individual package without refrigeration instructions that had been left unrefrigerated for 15 d. Storage of the product at ambient temperature likely allowed botulism spores to produce botulinum toxin, resulting in severe illness and death. The manufacturer improved labeling in response to this outbreak. Public health officials should consider unrefrigerated potato products as a potential source of botulism; clinicians should consider botulism as a possible cause of paralytic illness.
2019 年 9 月,科罗拉多州埃尔帕索县的公共卫生部门接到通知,有 4 名患者因具有类似肉毒中毒的临床特征而到附近医院就诊,肉毒中毒是一种由肉毒神经毒素引起的瘫痪性疾病。一名患者在就诊后不久死亡;其他 3 名患者需要重症监护,但在接受肉毒抗毒素治疗后康复。所有患者的血清中均检测到 A 型肉毒毒素。进一步调查显示,所有 4 名患者都食用了一份含有从单个包装中烤制的商业土豆的食物,这些土豆没有冷藏说明,已经在室温下存放了 15 天。该产品在室温下储存可能使肉毒梭菌孢子产生肉毒毒素,导致严重疾病和死亡。制造商针对此次疫情改进了标签。公共卫生官员应将未冷藏的土豆制品视为肉毒中毒的潜在来源;临床医生应考虑肉毒中毒是导致瘫痪性疾病的可能原因。