Division of Cardiovascular Medicine, Louisiana State University School of Medicine, Shreveport, LA, USA.
Division of Cardiovascular Medicine, Saint Louis University School of Medicine, Saint Louis, MO, USA.
Curr Cardiol Rep. 2022 Oct;24(10):1287-1297. doi: 10.1007/s11886-022-01744-y. Epub 2022 Sep 24.
Paravalvular leak (PVL) is a relatively uncommon complication associated with prosthetic valve implantation. PVL can occasionally lead to serious adverse consequences such as congestive heart failure, infective endocarditis, and hemolytic anemia. Surgical re-operation carries a high mortality risk.
Transcatheter closure therapy provides a viable alternative for the treatment of this disorder with reasonable procedural and clinical success. The recent advent of hybrid imaging modalities has increased procedural success. This article summarizes the pathophysiology, clinical characteristics, and treatment modalities surroundings prosthetic paravalvular leak.
瓣周漏（PVL）是一种与人工瓣膜植入相关的相对少见的并发症。瓣周漏偶尔可导致严重不良后果，如充血性心力衰竭、感染性心内膜炎和溶血性贫血。再次手术风险较高。
经导管封堵治疗为该疾病的治疗提供了一种可行的替代方案，具有合理的操作成功率和临床成功率。最近杂交成像技术的出现提高了操作成功率。本文总结了人工瓣周漏的病理生理学、临床特征和治疗方式。
