钙钛矿量子点作为一种化学发光平台，用于头孢唑林的高灵敏度检测。

Perovskite quantum dots as a chemiluminescence platform for highly sensitive assay of cefazolin.

机构信息

Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz 5166616471, Iran.

出版信息

Spectrochim Acta A Mol Biomol Spectrosc. 2023 Jan 15;285:121845. doi: 10.1016/j.saa.2022.121845. Epub 2022 Sep 17.

DOI:10.1016/j.saa.2022.121845

Abstract

This paper reports on a chemiluminescence (CL) probe consist of CsPbBr quantum dots (QDs) in organic phase together with Fe(II) and KSO in aqueous medium for the highly selective and sensitive determination of the antibiotic, cefazolin (CFZ). The CsPbBrperovskite QDs prepared by the ligand assisted reprecipitation method, exhibit a narrow fluorescence at 533 nm under 460 nm excitation with a high quantum yield (42 %). The Fe(II) - SO as an ultra-weak CL system is converted to a rather strong CL sensing platform in the presence of organic-phase CsPbBr QDs. It was observed that CFZ exerts an enhancement effect on the CL signal of the designed probe in the linear range of 25 - 300 nM, with a low limit of detection (9.6 nM). The introduced sensor has broad application prospects in biosensing, food detection, and other fields with recovery ranging from 94 to 106 %.

摘要

本文报道了一种化学发光（CL）探针，由有机相中的 CsPbBr 量子点（QDs）与 Fe(II)和 KSO 在水相中组成，用于高度选择性和灵敏地测定抗生素头孢唑林（CFZ）。通过配体辅助再沉淀法制备的 CsPbBr 钙钛矿量子点在 460nm 激发下于 533nm 处呈现窄荧光，量子产率高达 42%。Fe(II) - SO 作为超弱 CL 体系，在存在有机相 CsPbBr QDs 的情况下转化为相当强的 CL 传感平台。结果表明，CFZ 在 25-300nm 的线性范围内对设计探针的 CL 信号具有增强作用，检测限低至 9.6nm。该传感器在生物传感、食品检测等领域具有广阔的应用前景，回收率在 94%至 106%之间。