Tedrus G M A S, Souza D C M, Crepaldi C R, Petrarca Y M
Pontifical Catholic University of Campinas, Campinas, SP, Brazil.
Pontifical Catholic University of Campinas, Campinas, SP, Brazil.
Rev Neurol (Paris). 2023 Mar;179(3):183-187. doi: 10.1016/j.neurol.2022.05.009. Epub 2022 Sep 22.
To explore the relationship between suicide risk, the perception of social support and quality of life (QoL), and with the clinical variables of adult people with epilepsy (PWEs).
A total of 98 consecutive PWEs cared for in the outpatient setting, with a mean age of 48.1±15.9 years, having had epilepsy for 26.4±16.4 years and 48 (48.9%) female cases participated in this study. The MINI suicide module, the Social support satisfaction scale (SSSS), the Quality of life in epilepsy inventory (QOLIE-31), and the Hospital anxiety and depression scale (HADS) were used. A logistic regression was conducted to assess the factors associated with the suicide risk.
Suicide risk was present in 33 cases. Younger age, earlier age at epilepsy onset, depression and anxiety in the HADS scale, and lower MMSE, QOLIE-31, and SSSS scores were significantly associated with suicide risk in the univariate analysis. The logistic regression analysis identified that lower scores in the MMSE (OR 0.826, 95%CI 0.705-0.969), presence of anxiety (OR 0.197, CI 0.073-0.530), and a low perception regarding satisfaction with family (OR 0.953, CI 0.920-0.988) are the factors associated with the highest risk of suicide.
Suicide risk and recurrence of a suicide attempt was high in the PWEs. Suicide risk was associated with clinical variables, the presence of anxiety and the perception of less social support from the family.
探讨癫痫成年患者(PWEs)的自杀风险、社会支持感知与生活质量(QoL)之间的关系,以及与临床变量的关系。
本研究共纳入98例在门诊接受治疗的连续PWEs,平均年龄48.1±15.9岁,癫痫病程26.4±16.4年,其中48例(48.9%)为女性。使用了MINI自杀模块、社会支持满意度量表(SSSS)、癫痫生活质量量表(QOLIE-31)和医院焦虑抑郁量表(HADS)。进行逻辑回归分析以评估与自杀风险相关的因素。
33例存在自杀风险。单因素分析显示,年龄较小、癫痫发病年龄较早、HADS量表中的抑郁和焦虑、较低的MMSE、QOLIE-31和SSSS评分与自杀风险显著相关。逻辑回归分析确定,MMSE得分较低(OR 0.826,95%CI 0.705-0.969)、存在焦虑(OR 0.197,CI 0.073-0.530)以及对家庭满意度的低感知(OR 0.953,CI 0.920-0.988)是与最高自杀风险相关的因素。
PWEs的自杀风险和自杀未遂复发率较高。自杀风险与临床变量、焦虑的存在以及来自家庭的社会支持较少的感知有关。