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眼眶结核:一例病例报告及影像学在治疗中的作用更新。

Orbital tuberculosis: a case report and update on the role of imaging in treatment.

机构信息

Department of Ophthalmology, Columbia University College of Physicians and Surgeons, New York, New York, USA.

Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, NewYork Presbyterian Hospital, New York, New York, USA.

出版信息

Orbit. 2024 Jun;43(3):344-349. doi: 10.1080/01676830.2022.2126499. Epub 2022 Sep 26.

Abstract

Orbital tuberculosis is a manifestation of extra-pulmonary tuberculosis that is challenging to diagnose and treat. Here, we describe the pivotal role of serial imaging in the diagnosis and treatment of orbital tuberculosis. A 28-year-old male presented with recurrent right upper eyelid swelling and a supraduction deficit associated with a firm painless orbital mass, seen on initial computed tomography to be an extensive superomedial lesion producing mass effect. Biopsy revealed a tuberculosis-like granulomatous inflammation, which, coupled with a positive QuantiFERON gold test, led to empiric anti-tuberculin treatment. Serial radiologic imaging following initiation of treatment showed progressive reduction in mass size, supporting the diagnosis and determining the length of treatment. This rare case demonstrates the utility of serial radiologic exams in the diagnosis and treatment of orbital tuberculosis.

摘要

眼眶结核是肺外结核的一种表现形式,其诊断和治疗具有挑战性。在这里,我们描述了连续影像学在眼眶结核的诊断和治疗中的关键作用。一名 28 岁男性因反复发作的右上眼睑肿胀和上转障碍伴眶内硬性无痛肿块就诊,最初的计算机断层扫描显示为广泛的内侧病变,产生肿块效应。活检显示类似结核的肉芽肿性炎症,结合 QuantiFERON gold 试验阳性,导致经验性抗结核治疗。治疗开始后连续的影像学检查显示肿块大小逐渐缩小,支持了诊断并确定了治疗时间。这个罕见病例说明了连续影像学检查在眼眶结核的诊断和治疗中的应用价值。

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