Chris O'Brien Lifehouse Comprehensive Cancer Centre, Sydney, NSW, Australia.
Western Sydney University, Sydney, NSW, Australia.
Integr Cancer Ther. 2022 Jan-Dec;21:15347354221123055. doi: 10.1177/15347354221123055.
Around three quarters of individuals undergoing chemotherapy self-report multiple symptoms. There is clinical trial evidence of effectiveness for acupuncture for commonly experienced symptoms, and emerging evidence for reflexology, but little is known about the effects of these therapies on multiple symptoms when implemented in a real world setting during active chemotherapy treatment.
This was a cohort study of participants receiving reflexology and/or acupuncture while attending chemotherapy. Participants received a 20 minute reflexology treatment or a 20 minute acupuncture treatment or a combination of both. Patient reported outcome measures were administered before and after the treatment using the Edmonton Symptom Assessment Scale (ESAS).
During the study period, 330 unique patients received a total of 809 acupuncture and/or reflexology treatments. Participants had, on average, 5.3 symptoms each which they reported as moderate to severe (≥4/10) using the ESAS at baseline. Following treatment, participants reported 3.2 symptoms as moderate to severe. The symptom change for all participant encounters receiving any therapy was statistically significant for all symptoms, and clinically significant (a reduction of more than 1) for all symptoms except financial distress, appetite, and memory. Clinically significant levels of global distress (<3) were reduced in 72% of all participants receiving either therapy. No adverse events were recorded.
The results indicate that acupuncture and reflexology administered alongside chemotherapy may reduce patient reported symptom burden and patient global symptom related distress. Future research would include an active control group, and consider confounding factors such as chemotherapy stage and medication.
在接受化疗的人群中,有四分之三的人自述存在多种症状。有临床试验证据表明,针灸和反射疗法对常见症状有效,而反射疗法也有新的证据表明有效,但在化疗治疗期间,在真实环境中实施这些疗法对多种症状的影响知之甚少。
这是一项针对接受反射疗法和/或针灸治疗的化疗患者的队列研究。患者接受 20 分钟的反射疗法治疗或 20 分钟的针灸治疗,或两者结合。在治疗前后使用埃德蒙顿症状评估量表(ESAS)进行患者报告的结局测量。
在研究期间,330 名独特的患者共接受了 809 次针灸和/或反射疗法治疗。参与者平均有 5.3 种症状,他们在基线时使用 ESAS 报告为中度至重度(≥4/10)。治疗后,参与者报告有 3.2 种症状为中度至重度。所有接受任何治疗的参与者的症状变化在所有症状上均具有统计学意义,且除经济困扰、食欲和记忆外,所有症状均具有临床意义(减少超过 1)。接受任何一种治疗的 72%的参与者的全球症状相关困扰(<3)水平均显著降低。未记录到不良反应。
结果表明,在化疗期间同时进行针灸和反射疗法可能会减轻患者报告的症状负担和患者的整体症状相关困扰。未来的研究将包括一个活性对照组,并考虑化疗阶段和药物等混杂因素。