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Galectin-3 Inhibition in COVID-19.

作者信息

Reddy Kiran, Nichol Alistair, McAuley Daniel F

机构信息

School of Medicine, Dentistry and Biomedical Sciences Queen's University Belfast Belfast, Northern Ireland.

Regional Intensive Care Unit Royal Victoria Hospital Belfast, Northern Ireland.

出版信息

Am J Respir Crit Care Med. 2023 Jan 15;207(2):118-120. doi: 10.1164/rccm.202209-1758ED.

Abstract
摘要

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本文引用的文献

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An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis: A Phase Ib/IIa Randomized Controlled Clinical Trial (DEFINE).
Am J Respir Crit Care Med. 2023 Jan 15;207(2):138-149. doi: 10.1164/rccm.202203-0477OC.
2
SARS-CoV-2 pathogenesis.
Nat Rev Microbiol. 2022 May;20(5):270-284. doi: 10.1038/s41579-022-00713-0. Epub 2022 Mar 30.
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Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19.
N Engl J Med. 2021 Apr 22;384(16):1491-1502. doi: 10.1056/NEJMoa2100433. Epub 2021 Feb 25.
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YKL-40 as a new promising prognostic marker of severity in COVID infection.
Crit Care. 2021 Feb 16;25(1):66. doi: 10.1186/s13054-020-03383-7.
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Hyperinflammation and Fibrosis in Severe COVID-19 Patients: Galectin-3, a Target Molecule to Consider.
Front Immunol. 2020 Aug 18;11:2069. doi: 10.3389/fimmu.2020.02069. eCollection 2020.
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COVID19 coagulopathy in Caucasian patients.
Br J Haematol. 2020 Jun;189(6):1044-1049. doi: 10.1111/bjh.16749. Epub 2020 May 17.
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The Many Roles of Galectin-3, a Multifaceted Molecule, in Innate Immune Responses against Pathogens.
Mediators Inflamm. 2017;2017:9247574. doi: 10.1155/2017/9247574. Epub 2017 May 11.
10
The Predictive Value of Plasma Galectin-3 for Ards Severity and Clinical Outcome.
Shock. 2017 Mar;47(3):331-336. doi: 10.1097/SHK.0000000000000757.

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