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微生物组分析:一种新兴的法医学调查工具。

Microbiome analysis: An emerging forensic investigative tool.

机构信息

Department of Forensic Science, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, India.

Department of Forensic Science, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, India.

出版信息

Forensic Sci Int. 2022 Nov;340:111462. doi: 10.1016/j.forsciint.2022.111462. Epub 2022 Sep 11.

DOI:10.1016/j.forsciint.2022.111462
PMID:36155349
Abstract

Microbial diversity's potential has been investigated in medical and therapeutic studies throughout the last few decades. However, its usage in forensics is increasing due to its effectiveness in circumstances when traditional approaches fail to provide a decisive opinion or are insufficient in forming a concrete opinion. The application of human microbiome may serve in detecting the type of stains of saliva and vaginal fluid, as well as in attributing the stains to the individual. Similarly, the microbiome makeup of a soil sample may be utilised to establish geographic origin or to associate humans, animals, or things with a specific area, additionally microorganisms influence the decay process which may be used in depicting the Time Since death. Further in detecting the traces of the amount and concentration of alcohol, narcotics, and other forensically relevant compounds in human body or visceral tissues as they also affect the microbial community within human body. Beside these, there is much more scope of microbiomes to be explored in terms of forensic investigation, this review focuses on multidimensional approaches to human microbiomes from a forensic standpoint, implying the potential of microbiomes as an emerging tool for forensic investigations such as individual variability via skin microbiomes, reconstructing crime scene, and linking evidence to individual.

摘要

在过去的几十年里,医学和治疗研究已经探索了微生物多样性的潜力。然而,由于其在传统方法无法提供决定性意见或在形成具体意见时不够充分的情况下的有效性,其在法医学中的应用正在增加。人类微生物组的应用可用于检测唾液和阴道液的污渍类型,并将污渍归因于个人。同样,土壤样本的微生物组组成可用于确定地理来源或将人与动物或物与特定区域联系起来,此外,微生物会影响可能用于描述死亡时间的腐烂过程。此外,还可以在检测人体或内脏组织中酒精、麻醉品和其他法医学相关化合物的量和浓度的痕迹,因为它们也会影响人体内的微生物群落。除此之外,微生物组在法医调查方面还有更多的探索空间,本综述从法医学的角度重点介绍了人类微生物组的多维方法,暗示了微生物组作为法医调查新兴工具的潜力,例如通过皮肤微生物组来研究个体变异性、重建犯罪现场以及将证据与个人联系起来。

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Microbiome analysis: An emerging forensic investigative tool.微生物组分析:一种新兴的法医学调查工具。
Forensic Sci Int. 2022 Nov;340:111462. doi: 10.1016/j.forsciint.2022.111462. Epub 2022 Sep 11.
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Microbes as forensic indicators.作为法医指标的微生物
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At the Interface of Life and Death: Post-mortem and Other Applications of Vaginal, Skin, and Salivary Microbiome Analysis in Forensics.在生死交界处:阴道、皮肤和唾液微生物组分析在法医学中的尸检及其他应用
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Forensic Analysis of Human Microbiome in Skin and Body Fluids Based on Geographic Location.基于地理位置的人体皮肤和体液微生物组的法医分析。
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Microbiomes in forensic botany: a review.法庭植物学中的微生物组:综述。
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Analysis of Microbial Communities: An Emerging Tool in Forensic Sciences.微生物群落分析:法医学中的一种新兴工具。
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Body fluids should be identified before estimating the time since deposition (TsD) in microbiome-based stain analyses for forensics.在基于微生物组的法医污渍分析中估算沉积时间 (TsD) 之前,应识别体液。
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Integrating the human microbiome in the forensic toolkit: Current bottlenecks and future solutions.将人类微生物组纳入法医工具包:当前的瓶颈与未来的解决方案
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Targeted sequencing of clade-specific markers from skin microbiomes for forensic human identification.用于法医人类识别的皮肤微生物群落进化枝特异性标记物的靶向测序。
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Changes in the microbial community of semen exposed to different simulated forensic situations.暴露于不同模拟法医情境下的精液微生物群落变化。
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