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微生物组分析:一种新兴的法医学调查工具。

Microbiome analysis: An emerging forensic investigative tool.

机构信息

Department of Forensic Science, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, India.

Department of Forensic Science, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, India.

出版信息

Forensic Sci Int. 2022 Nov;340:111462. doi: 10.1016/j.forsciint.2022.111462. Epub 2022 Sep 11.

Abstract

Microbial diversity's potential has been investigated in medical and therapeutic studies throughout the last few decades. However, its usage in forensics is increasing due to its effectiveness in circumstances when traditional approaches fail to provide a decisive opinion or are insufficient in forming a concrete opinion. The application of human microbiome may serve in detecting the type of stains of saliva and vaginal fluid, as well as in attributing the stains to the individual. Similarly, the microbiome makeup of a soil sample may be utilised to establish geographic origin or to associate humans, animals, or things with a specific area, additionally microorganisms influence the decay process which may be used in depicting the Time Since death. Further in detecting the traces of the amount and concentration of alcohol, narcotics, and other forensically relevant compounds in human body or visceral tissues as they also affect the microbial community within human body. Beside these, there is much more scope of microbiomes to be explored in terms of forensic investigation, this review focuses on multidimensional approaches to human microbiomes from a forensic standpoint, implying the potential of microbiomes as an emerging tool for forensic investigations such as individual variability via skin microbiomes, reconstructing crime scene, and linking evidence to individual.

摘要

在过去的几十年里,医学和治疗研究已经探索了微生物多样性的潜力。然而,由于其在传统方法无法提供决定性意见或在形成具体意见时不够充分的情况下的有效性,其在法医学中的应用正在增加。人类微生物组的应用可用于检测唾液和阴道液的污渍类型,并将污渍归因于个人。同样,土壤样本的微生物组组成可用于确定地理来源或将人与动物或物与特定区域联系起来,此外,微生物会影响可能用于描述死亡时间的腐烂过程。此外,还可以在检测人体或内脏组织中酒精、麻醉品和其他法医学相关化合物的量和浓度的痕迹,因为它们也会影响人体内的微生物群落。除此之外,微生物组在法医调查方面还有更多的探索空间,本综述从法医学的角度重点介绍了人类微生物组的多维方法,暗示了微生物组作为法医调查新兴工具的潜力,例如通过皮肤微生物组来研究个体变异性、重建犯罪现场以及将证据与个人联系起来。

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