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两种评估青少年骨龄的简化方法比较:缩略骨龄法和 SickKids/Columbia 法。

A Comparison of 2 Abbreviated Methods for Assessing Adolescent Bone Age: The Shorthand Bone Age Method and the SickKids/Columbia Method.

机构信息

Departments of Orthopedics.

Division of Orthopaedic Surgery, Hospital for Sick Children, Toronto, ON, Canada.

出版信息

J Pediatr Orthop. 2023 Jan 1;43(1):e80-e85. doi: 10.1097/BPO.0000000000002269. Epub 2022 Sep 27.

Abstract

BACKGROUND

Radiographic assessment of bone age is critically important to decision-making on the type and timing of operative interventions in pediatric orthopaedics. The current widely accepted method for determining bone age is time and resource-intensive. This study sought to assess the reliability and accuracy of 2 abbreviated methods, the Shorthand Bone Age (SBA) and the SickKids/Columbia (SKC) methods, to the widely accepted Greulich and Pyle (GP) method.

METHODS

Standard posteroanterior radiographs of the left hand of 125 adolescent males and 125 adolescent females were compiled, with bone ages determined by the GP method ranging from 9 to 16 years for males and 8 to 14 years for females. Blinded to the chronologic age and GP bone age of each child, the bone age for each radiograph was determined using the SBA and SKC methods by an orthopaedic surgery resident, 2 pediatric orthopaedic surgeons, and a musculoskeletal radiologist. Measurements were then repeated 2 weeks later after rerandomization of the radiographs. Intrarater and interrater reliability for the 2 abbreviated methods as well as the agreement between all 3 methods were calculated using weighted κ values. Mean absolute differences between methods were also calculated.

RESULTS

Both bone age methods demonstrated substantial to almost perfect intrarater reliability, with a weighted κ ranging from 0.79 to 0.93 for the SBA method and from 0.82 to 0.96 for the SKC method. Interrater reliability was moderate to substantial (weighted κ: 0.55 to 0.84) for the SBA method and substantial to almost perfect (weighted κ: 0.67 to 0.92) for the SKC method. Agreement between the 3 methods was substantial for all raters and all comparisons. The mean absolute difference, been GP-derived and SBA-derived bone age, was 7.6±7.8 months, as compared with 8.8±7.4 months between GP-derived and SKC-derived bone ages.

CONCLUSIONS

The SBA and SKC methods have comparable reliability, and both correlate well to the widely accepted GP methods and to each other. However, they have relatively large absolute differences when compared with the GP method. These methods offer simple, efficient, and affordable estimates for bone age determination, but at best provide an estimate to be used in the appropriate setting.

LEVEL OF EVIDENCE

Diagnostic study-level III.

摘要

背景

骨龄的影像学评估对小儿矫形外科手术干预的类型和时机的决策至关重要。目前广泛接受的确定骨龄的方法既费时又费资源。本研究旨在评估两种简化方法(简写骨龄[SBA]和 SickKids/Columbia[SKC]方法)相对于广泛接受的 Greulich 和 Pyle[GP]方法的可靠性和准确性。

方法

收集了 125 名青少年男性和 125 名青少年女性的左手后前位 X 线片,男性的 GP 骨龄范围为 9 至 16 岁,女性的 GP 骨龄范围为 8 至 14 岁。在不知道每个孩子的实际年龄和 GP 骨龄的情况下,由一名矫形外科住院医师、两名小儿矫形外科医生和一名肌肉骨骼放射科医生使用 SBA 和 SKC 方法确定每个 X 线片的骨龄。然后在重新随机排列 X 线片后 2 周重复测量。使用加权κ值计算 2 种简化方法的组内和组间可靠性以及所有 3 种方法之间的一致性。还计算了方法之间的平均绝对差异。

结果

两种骨龄方法均显示出高度可靠至几乎完美的组内可靠性,SBA 方法的加权κ值范围为 0.79 至 0.93,SKC 方法的加权κ值范围为 0.82 至 0.96。SBA 方法的组间可靠性为中度至高度可靠(加权κ值:0.55 至 0.84),SKC 方法的组间可靠性为高度可靠至几乎完美(加权κ值:0.67 至 0.92)。所有评估者和所有比较的 3 种方法之间的一致性均为高度可靠。与 GP 衍生的 SBA 衍生骨龄相比,GP 衍生和 SKC 衍生骨龄之间的平均绝对差异为 7.6±7.8 个月,而与 GP 衍生和 SKC 衍生骨龄相比,GP 衍生和 SKC 衍生骨龄之间的平均绝对差异为 8.8±7.4 个月。

结论

SBA 和 SKC 方法具有相似的可靠性,与广泛接受的 GP 方法和彼此都有很好的相关性。然而,与 GP 方法相比,它们的绝对差异相对较大。这些方法提供了用于确定骨龄的简单、高效且经济实惠的估计值,但最好仅作为在适当环境下使用的估计值。

证据水平

诊断研究,III 级。

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