Medical School of Chinese PLA, Beijing, China.
Anhui Province PAP Corps Hospital, Hefei, China.
NeuroRehabilitation. 2022;51(3):527-532. doi: 10.3233/NRE-220132.
The lesions besides lateral ventricle and motor recovery following rehabilitation have hardly been studied.
To explore the relationship between the size, location of infarction beside the lateral ventricle and motor recovery following rehabilitation.
A prospective cohort of 55 patients submitted to a Rehabilitation Medical Center between January 2015 and June 2019 who suffered a single cerebral infarction beside the lateral ventricle were included in the study. The size and distance between the posterior margin and the frontal-middle line (FML) of the lesion were measured. Follow-up was conducted until the recovery was no longer progressing. Barthel index and Brunstrom stages were used to evaluate the outcome (full recovery, partial recovery and poor recovery). Variance analysis and nonparametric test were used for the comparison between groups. Multivariate logistic regression analysis was used to screen the factors affecting the outcomes. The Pearson correlation coefficient was used to compare the volume of infarction, behind the FML and the outcomes.
Among the 55 patients, the outcome was full recovery (n = 28), partial recovery (n = 13) and poor recovery (n = 14). Multivariate logistic regression analysis showed that volume and location of the infarction were significantly correlated with the outcome (p = 0.039, 0.050). The lesion volume in the full recovery patients was significantly smaller than that in the poor recovery patients (p < 0.01). The posterior edge of the lesion in the full recovery patients behind the FML was statistically significant compared with that in the poor recovery patients (p < 0.01). Spearman correlation analysis showed that the motor recovery was negative correlation to lesion volume (r = -0.508, P < 0.01) and location (r = -0.450, P < 0.01) of the infarction.
The motor recovery of patients with cerebral infarction beside lateral ventricle is related to the volume and location of the lesion. The larger the volume of the lesion, and the farther the posterior margin of the lesion to the FML, the worse the motor recovery.
侧脑室旁病灶及康复后运动功能恢复情况鲜有研究。
探讨侧脑室旁梗死病灶的大小、部位与康复后运动功能恢复的关系。
连续纳入 2015 年 1 月至 2019 年 6 月于康复医学中心就诊的单发性侧脑室旁脑梗死患者 55 例，测量病灶的大小和后缘距额中线（FML）的距离。随访至恢复不再进展。采用 Barthel 指数和 Brunstrom 分期评定预后（完全恢复、部分恢复和恢复不良）。方差分析和非参数检验比较组间差异，采用多因素 logistic 回归分析筛选影响预后的因素，采用 Pearson 相关系数比较梗死体积、距 FML 后缘距离与预后的相关性。
55 例患者中，预后完全恢复 28 例，部分恢复 13 例，恢复不良 14 例。多因素 logistic 回归分析显示，梗死体积和部位与预后显著相关（P = 0.039、0.050）。完全恢复患者的梗死体积显著小于恢复不良患者（P < 0.01），完全恢复患者病灶后缘距 FML 显著大于恢复不良患者（P < 0.01）。Spearman 相关分析显示，运动功能恢复与梗死体积（r = -0.508，P < 0.01）和部位（r = -0.450，P < 0.01）呈负相关。
侧脑室旁脑梗死患者的运动功能恢复与病灶的体积和部位有关，病灶体积越大、后缘距 FML 越远，运动功能恢复越差。
Zotero 插件